The Pathophysiology and Management of Diabetic Ketoacidosis in COVID-19 Patients: A Literature Review

Diabetic individuals are considered a vulnerable population during the COVID-19 Pandemic, and several studies noted worse outcomes, including death, among those who get infected. Diabetic emergencies, such as ketoacidosis (DKA), are common and potentially life-threatening conditions in uncontrolled...

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Main Authors: Tilinca Mariana Cornelia, Gliga Maximilian Cosma, Varga Andreea
Format: Article
Language:English
Published: Sciendo 2021-11-01
Series:The Journal of Critical Care Medicine
Subjects:
Online Access:https://doi.org/10.2478/jccm-2021-0024
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author Tilinca Mariana Cornelia
Gliga Maximilian Cosma
Varga Andreea
author_facet Tilinca Mariana Cornelia
Gliga Maximilian Cosma
Varga Andreea
author_sort Tilinca Mariana Cornelia
collection DOAJ
description Diabetic individuals are considered a vulnerable population during the COVID-19 Pandemic, and several studies noted worse outcomes, including death, among those who get infected. Diabetic emergencies, such as ketoacidosis (DKA), are common and potentially life-threatening conditions in uncontrolled patients. While the pathophysiological background of the relationship between COVID-19 and DKA is not fully understood, early reports available so far indicate that patients with pre-existing diabetes who get infected with the SARS-CoV 2 virus are at higher risk of DKA. It was also suggested that DKA is a poor prognostic sign for infected patients, these being at higher risk of developing worse forms of COVID-19 disease and having high mortality. Therefore, healthcare personnel dealing with such patients face a considerable challenge, as the correct and safe emergency management of such cases is far from established. This article aimed to conduct a study that reviews the current published data available about patients with DKA and COVID-19.
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spelling doaj.art-24237396815d4d49830827ceb177d5822023-12-03T06:45:18ZengSciendoThe Journal of Critical Care Medicine2393-18172021-11-018161310.2478/jccm-2021-0024The Pathophysiology and Management of Diabetic Ketoacidosis in COVID-19 Patients: A Literature ReviewTilinca Mariana Cornelia0Gliga Maximilian Cosma1Varga Andreea2George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Targu Mures, RomaniaMures County Hospital, Targu Mures, RomaniaGeorge Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Targu Mures, RomaniaDiabetic individuals are considered a vulnerable population during the COVID-19 Pandemic, and several studies noted worse outcomes, including death, among those who get infected. Diabetic emergencies, such as ketoacidosis (DKA), are common and potentially life-threatening conditions in uncontrolled patients. While the pathophysiological background of the relationship between COVID-19 and DKA is not fully understood, early reports available so far indicate that patients with pre-existing diabetes who get infected with the SARS-CoV 2 virus are at higher risk of DKA. It was also suggested that DKA is a poor prognostic sign for infected patients, these being at higher risk of developing worse forms of COVID-19 disease and having high mortality. Therefore, healthcare personnel dealing with such patients face a considerable challenge, as the correct and safe emergency management of such cases is far from established. This article aimed to conduct a study that reviews the current published data available about patients with DKA and COVID-19.https://doi.org/10.2478/jccm-2021-0024covid-19diabetesketoacidosispandemicpathogenesis
spellingShingle Tilinca Mariana Cornelia
Gliga Maximilian Cosma
Varga Andreea
The Pathophysiology and Management of Diabetic Ketoacidosis in COVID-19 Patients: A Literature Review
The Journal of Critical Care Medicine
covid-19
diabetes
ketoacidosis
pandemic
pathogenesis
title The Pathophysiology and Management of Diabetic Ketoacidosis in COVID-19 Patients: A Literature Review
title_full The Pathophysiology and Management of Diabetic Ketoacidosis in COVID-19 Patients: A Literature Review
title_fullStr The Pathophysiology and Management of Diabetic Ketoacidosis in COVID-19 Patients: A Literature Review
title_full_unstemmed The Pathophysiology and Management of Diabetic Ketoacidosis in COVID-19 Patients: A Literature Review
title_short The Pathophysiology and Management of Diabetic Ketoacidosis in COVID-19 Patients: A Literature Review
title_sort pathophysiology and management of diabetic ketoacidosis in covid 19 patients a literature review
topic covid-19
diabetes
ketoacidosis
pandemic
pathogenesis
url https://doi.org/10.2478/jccm-2021-0024
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