Prozone effects in microscopic agglutination tests for leptospirosis in the sera of mice infected with the pathogenic Leptospira interrogans serovar Canicola

Prozone effects in microscopic agglutination tests for leptospirosis in the sera of mice infected with the pathogenic Leptospira interrogans serovar Canicola

Mice experimentally infected with a pathogenic strain of Leptospira interrogans serovar Canicola produced false negative results (prozone effect) in a microscopic agglutination test (MAT). This prozone effect occurred in several serum samples collected at different post-infection times, but it was m...

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Bibliographic Details
Main Authors: Fabio Hiroto Shimabukuro, Veruska Maia da Costa, Rodrigo Costa da Silva, Hélio Langoni, Aristeu Vieira da Silva, Lídia Raquel de Carvalho, Paulo Francisco Domingues
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2013-08-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
microscopic agglutination test
prozone effect
leptospirosis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000500668&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000500668&lng=en&tlng=en

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