Cell-based meat: The molecular aspect
Cellular agriculture is one of the evolving fields of translational biotechnology. The emerging science aims to improve the issues related to sustainable food products and food security, reduce greenhouse gas emissions and provide animal wellbeing by circumventing livestock farming through cell-base...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-03-01
|
| Series: | Frontiers in Food Science and Technology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/frfst.2023.1126455/full |
| _version_ | 1797856129357709312 |
|---|---|
| author | Asim Azhar Md. Zeyaullah Shushruta Bhunia Santhosh Kacham Girish Patil Khursheed Muzammil Mohammad Suhail Khan Sandeep Sharma Sandeep Sharma |
| author_facet | Asim Azhar Md. Zeyaullah Shushruta Bhunia Santhosh Kacham Girish Patil Khursheed Muzammil Mohammad Suhail Khan Sandeep Sharma Sandeep Sharma |
| author_sort | Asim Azhar |
| collection | DOAJ |
| description | Cellular agriculture is one of the evolving fields of translational biotechnology. The emerging science aims to improve the issues related to sustainable food products and food security, reduce greenhouse gas emissions and provide animal wellbeing by circumventing livestock farming through cell-based meat (CBM) production. CBM exploits cell culture techniques and biomanufacturing methods by manipulating mammalian, avian, and fish cell lines. The cell-based products ought to successfully meet the demand for nutritional protein products for human consumption and pet animals. However, substantial advancement and modification are required for manufacturing CBM and related products in terms of cost, palatability, consumer acceptance, and safety. In order to achieve high-quality CBM and its production with high yield, the molecular aspect needs a thorough inspection to achieve good laboratory practices for commercial production. The current review discusses various aspects of molecular biology involved in establishing cell lines, myogenesis, regulation, scaffold, and bioreactor-related approaches to achieve the target of CBM. |
| first_indexed | 2024-04-09T20:35:22Z |
| format | Article |
| id | doaj.art-24289a69324f4ce5b36f58813f3ab373 |
| institution | Directory Open Access Journal |
| issn | 2674-1121 |
| language | English |
| last_indexed | 2024-04-09T20:35:22Z |
| publishDate | 2023-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Food Science and Technology |
| spelling | doaj.art-24289a69324f4ce5b36f58813f3ab3732023-03-30T09:23:35ZengFrontiers Media S.A.Frontiers in Food Science and Technology2674-11212023-03-01310.3389/frfst.2023.11264551126455Cell-based meat: The molecular aspectAsim Azhar0Md. Zeyaullah1Shushruta Bhunia2Santhosh Kacham3Girish Patil4Khursheed Muzammil5Mohammad Suhail Khan6Sandeep Sharma7Sandeep Sharma8Neat Meatt Biotech Pvt. Ltd., New Delhi, IndiaDepartment of Basic Medical Science, College of Applied Medical Sciences, Khamis Mushayt Campus, King Khalid University (KKU), Abha, Saudi ArabiaNeat Meatt Biotech Pvt. Ltd., New Delhi, IndiaAtal Incubation Center, Center for Cellular and Molecular Biology, Hyderabad, IndiaNational Research Centre on Mithun, Dimapur, Nagaland, IndiaDepartment of Public Health, College of Applied Medical Sciences, Khamis Mushayt Campus, King Khalid University (KKU), Abha, Saudi ArabiaDepartment of Public Health, College of Applied Medical Sciences, Khamis Mushayt Campus, King Khalid University (KKU), Abha, Saudi ArabiaNeat Meatt Biotech Pvt. Ltd., New Delhi, IndiaAtal Incubation Center, Center for Cellular and Molecular Biology, Hyderabad, IndiaCellular agriculture is one of the evolving fields of translational biotechnology. The emerging science aims to improve the issues related to sustainable food products and food security, reduce greenhouse gas emissions and provide animal wellbeing by circumventing livestock farming through cell-based meat (CBM) production. CBM exploits cell culture techniques and biomanufacturing methods by manipulating mammalian, avian, and fish cell lines. The cell-based products ought to successfully meet the demand for nutritional protein products for human consumption and pet animals. However, substantial advancement and modification are required for manufacturing CBM and related products in terms of cost, palatability, consumer acceptance, and safety. In order to achieve high-quality CBM and its production with high yield, the molecular aspect needs a thorough inspection to achieve good laboratory practices for commercial production. The current review discusses various aspects of molecular biology involved in establishing cell lines, myogenesis, regulation, scaffold, and bioreactor-related approaches to achieve the target of CBM.https://www.frontiersin.org/articles/10.3389/frfst.2023.1126455/fullcell-based meatbioreactormuscle cellstem cellcell lines |
| spellingShingle | Asim Azhar Md. Zeyaullah Shushruta Bhunia Santhosh Kacham Girish Patil Khursheed Muzammil Mohammad Suhail Khan Sandeep Sharma Sandeep Sharma Cell-based meat: The molecular aspect Frontiers in Food Science and Technology cell-based meat bioreactor muscle cell stem cell cell lines |
| title | Cell-based meat: The molecular aspect |
| title_full | Cell-based meat: The molecular aspect |
| title_fullStr | Cell-based meat: The molecular aspect |
| title_full_unstemmed | Cell-based meat: The molecular aspect |
| title_short | Cell-based meat: The molecular aspect |
| title_sort | cell based meat the molecular aspect |
| topic | cell-based meat bioreactor muscle cell stem cell cell lines |
| url | https://www.frontiersin.org/articles/10.3389/frfst.2023.1126455/full |
| work_keys_str_mv | AT asimazhar cellbasedmeatthemolecularaspect AT mdzeyaullah cellbasedmeatthemolecularaspect AT shushrutabhunia cellbasedmeatthemolecularaspect AT santhoshkacham cellbasedmeatthemolecularaspect AT girishpatil cellbasedmeatthemolecularaspect AT khursheedmuzammil cellbasedmeatthemolecularaspect AT mohammadsuhailkhan cellbasedmeatthemolecularaspect AT sandeepsharma cellbasedmeatthemolecularaspect AT sandeepsharma cellbasedmeatthemolecularaspect |