Structural and Pharmacological Effects of Ring-Closing Metathesis in Peptides
Applications of ring-closing alkene metathesis (RCM) in acyclic α- and β-peptides and closely related systems are reviewed, with a special emphasis on the structural and pharmacological effects of cyclization by RCM.
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2010-09-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1420-3049/15/9/6638/ |
| _version_ | 1828816698356006912 |
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| author | Pål Rongved Øyvind Jacobsen Jo Klaveness |
| author_facet | Pål Rongved Øyvind Jacobsen Jo Klaveness |
| author_sort | Pål Rongved |
| collection | DOAJ |
| description | Applications of ring-closing alkene metathesis (RCM) in acyclic α- and β-peptides and closely related systems are reviewed, with a special emphasis on the structural and pharmacological effects of cyclization by RCM. |
| first_indexed | 2024-12-12T11:10:16Z |
| format | Article |
| id | doaj.art-242fa582408245af94d352776358700d |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-12T11:10:16Z |
| publishDate | 2010-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-242fa582408245af94d352776358700d2022-12-22T00:26:19ZengMDPI AGMolecules1420-30492010-09-011596638667710.3390/molecules15096638Structural and Pharmacological Effects of Ring-Closing Metathesis in PeptidesPål RongvedØyvind JacobsenJo KlavenessApplications of ring-closing alkene metathesis (RCM) in acyclic α- and β-peptides and closely related systems are reviewed, with a special emphasis on the structural and pharmacological effects of cyclization by RCM.http://www.mdpi.com/1420-3049/15/9/6638/ring-closing metathesispeptidesstructurepharmacological properties |
| spellingShingle | Pål Rongved Øyvind Jacobsen Jo Klaveness Structural and Pharmacological Effects of Ring-Closing Metathesis in Peptides Molecules ring-closing metathesis peptides structure pharmacological properties |
| title | Structural and Pharmacological Effects of Ring-Closing Metathesis in Peptides |
| title_full | Structural and Pharmacological Effects of Ring-Closing Metathesis in Peptides |
| title_fullStr | Structural and Pharmacological Effects of Ring-Closing Metathesis in Peptides |
| title_full_unstemmed | Structural and Pharmacological Effects of Ring-Closing Metathesis in Peptides |
| title_short | Structural and Pharmacological Effects of Ring-Closing Metathesis in Peptides |
| title_sort | structural and pharmacological effects of ring closing metathesis in peptides |
| topic | ring-closing metathesis peptides structure pharmacological properties |
| url | http://www.mdpi.com/1420-3049/15/9/6638/ |
| work_keys_str_mv | AT palrongved structuralandpharmacologicaleffectsofringclosingmetathesisinpeptides AT øyvindjacobsen structuralandpharmacologicaleffectsofringclosingmetathesisinpeptides AT joklaveness structuralandpharmacologicaleffectsofringclosingmetathesisinpeptides |