Rationale, design and methodology of the RAMSES Study: ReAl-life Multicenter Survey Evaluating Stroke Prevention Strategies
Objective: Atrial fibrillation is the most common arrhythmia and is associated with a five- fold increased risk of thromboembolic events. Vitamin K antagonists (VKAs) have been the mainstay of oral anticoagulant prophylaxis and the data on stroke prevention strategies are limited to VKA era. The pu...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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KARE Publishing
2016-05-01
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| Series: | Türk Kardiyoloji Derneği Arşivi |
| Subjects: | |
| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-29266 |
| _version_ | 1797920350045995008 |
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| author | Özcan Başaran Volkan Dogan Kadriye Memic Sancar İbrahim Altun Kadir Ugur Mert Gurbet Özge Mert Nesrin Filiz Başaran Edip Güvenç Çekiç Cevat Kırma Murat Biteker |
| author_facet | Özcan Başaran Volkan Dogan Kadriye Memic Sancar İbrahim Altun Kadir Ugur Mert Gurbet Özge Mert Nesrin Filiz Başaran Edip Güvenç Çekiç Cevat Kırma Murat Biteker |
| author_sort | Özcan Başaran |
| collection | DOAJ |
| description | Objective: Atrial fibrillation is the most common arrhythmia and is associated with a five- fold increased risk of thromboembolic events. Vitamin K antagonists (VKAs) have been the mainstay of oral anticoagulant prophylaxis and the data on stroke prevention strategies are limited to VKA era. The purpose of this study is to evaluate the use of VKA, non-Vitamin K antagonist oral anticoagulants (NOAC), and antiplatelet agents in patients with non-valvular atrial fibrillation (NVAF).
Methods: The ReAl-life Multicenter Survey Evaluating Stroke prevention strategies in Turkey (RAMSES) is an observational, multicenter, prospective study of patients with NVAF. The study targeted enrollment of 7835 patients from 68 sites in Turkey. All the data will be collected at one point in time and current clinical practice will be evaluated. (ClinicalTrials.gov number NCT02344901).
Results: Baseline characteristics of patients, antithrombotic therapies, transition to NOACs and rate/rhythm control strategies will be evaluated.
Conclusion: The RAMSES registry will be the largest study in Turkish NVAF patients. The study will provide insights into real-world problems and anticoagulant treatment in patients with NVAF. |
| first_indexed | 2024-04-10T13:59:42Z |
| format | Article |
| id | doaj.art-242ff1b195aa45769a1ddde7cbdae33f |
| institution | Directory Open Access Journal |
| issn | 1016-5169 |
| language | English |
| last_indexed | 2024-04-10T13:59:42Z |
| publishDate | 2016-05-01 |
| publisher | KARE Publishing |
| record_format | Article |
| series | Türk Kardiyoloji Derneği Arşivi |
| spelling | doaj.art-242ff1b195aa45769a1ddde7cbdae33f2023-02-15T16:10:19ZengKARE PublishingTürk Kardiyoloji Derneği Arşivi1016-51692016-05-0144321522010.5543/tkda.2015.29266TKDA-29266Rationale, design and methodology of the RAMSES Study: ReAl-life Multicenter Survey Evaluating Stroke Prevention StrategiesÖzcan Başaran0Volkan Dogan1Kadriye Memic Sancar2İbrahim Altun3Kadir Ugur Mert4Gurbet Özge Mert5Nesrin Filiz Başaran6Edip Güvenç Çekiç7Cevat Kırma8Murat Biteker9Department Of Cardiology, Mugla Sitki Kocman University Faculty Of Medicine, Mugla, TurkeyDepartment Of Cardiology, Mugla Sitki Kocman University Faculty Of Medicine, Mugla, TurkeyDepartment Of Cardiology, Mugla Sitki Kocman University Faculty Of Medicine, Mugla, TurkeyDepartment Of Cardiology, Mugla Sitki Kocman University Faculty Of Medicine, Mugla, TurkeyDepartment Of Cardiology, Mugla Sitki Kocman University Faculty Of Medicine, Mugla, TurkeyDepartment Of Cardiology, Mugla Sitki Kocman University Faculty Of Medicine, Mugla, TurkeyDepartment Of Pharmacology, Mugla Sitki Kocman University Faculty Of Medicine, Mugla, TurkeyDepartment Of Pharmacology, Mugla Sitki Kocman University Faculty Of Medicine, Mugla, TurkeyDepartment of Cardiology, Kartal Kosuyolu Heart Training and Research Hospital, Istanbul, TurkeyDepartment Of Cardiology, Mugla Sitki Kocman University Faculty Of Medicine, Mugla, TurkeyObjective: Atrial fibrillation is the most common arrhythmia and is associated with a five- fold increased risk of thromboembolic events. Vitamin K antagonists (VKAs) have been the mainstay of oral anticoagulant prophylaxis and the data on stroke prevention strategies are limited to VKA era. The purpose of this study is to evaluate the use of VKA, non-Vitamin K antagonist oral anticoagulants (NOAC), and antiplatelet agents in patients with non-valvular atrial fibrillation (NVAF). Methods: The ReAl-life Multicenter Survey Evaluating Stroke prevention strategies in Turkey (RAMSES) is an observational, multicenter, prospective study of patients with NVAF. The study targeted enrollment of 7835 patients from 68 sites in Turkey. All the data will be collected at one point in time and current clinical practice will be evaluated. (ClinicalTrials.gov number NCT02344901). Results: Baseline characteristics of patients, antithrombotic therapies, transition to NOACs and rate/rhythm control strategies will be evaluated. Conclusion: The RAMSES registry will be the largest study in Turkish NVAF patients. The study will provide insights into real-world problems and anticoagulant treatment in patients with NVAF.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-29266atrial fibrillationoral anticoagulant; risk scores; stroke; turkey |
| spellingShingle | Özcan Başaran Volkan Dogan Kadriye Memic Sancar İbrahim Altun Kadir Ugur Mert Gurbet Özge Mert Nesrin Filiz Başaran Edip Güvenç Çekiç Cevat Kırma Murat Biteker Rationale, design and methodology of the RAMSES Study: ReAl-life Multicenter Survey Evaluating Stroke Prevention Strategies Türk Kardiyoloji Derneği Arşivi atrial fibrillation oral anticoagulant; risk scores; stroke; turkey |
| title | Rationale, design and methodology of the RAMSES Study: ReAl-life Multicenter Survey Evaluating Stroke Prevention Strategies |
| title_full | Rationale, design and methodology of the RAMSES Study: ReAl-life Multicenter Survey Evaluating Stroke Prevention Strategies |
| title_fullStr | Rationale, design and methodology of the RAMSES Study: ReAl-life Multicenter Survey Evaluating Stroke Prevention Strategies |
| title_full_unstemmed | Rationale, design and methodology of the RAMSES Study: ReAl-life Multicenter Survey Evaluating Stroke Prevention Strategies |
| title_short | Rationale, design and methodology of the RAMSES Study: ReAl-life Multicenter Survey Evaluating Stroke Prevention Strategies |
| title_sort | rationale design and methodology of the ramses study real life multicenter survey evaluating stroke prevention strategies |
| topic | atrial fibrillation oral anticoagulant; risk scores; stroke; turkey |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-29266 |
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