Vaccination timeliness and delay in low- and middle-income countries: a systematic review of the literature, 2007-2017

Background: Traditional measurements of vaccine coverage at specific ages can mask poor vaccine timeliness. However, optimal measurement of timing is unclear due to variations in countries’ recommended vaccination schedules and lack of a commonly accepted standard for “timeliness”. We conducted a sy...

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Main Authors: Nina B. Masters, Abram L. Wagner, Matthew L. Boulton
Format: Article
Language:English
Published: Taylor & Francis Group 2019-12-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:http://dx.doi.org/10.1080/21645515.2019.1616503
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author Nina B. Masters
Abram L. Wagner
Matthew L. Boulton
author_facet Nina B. Masters
Abram L. Wagner
Matthew L. Boulton
author_sort Nina B. Masters
collection DOAJ
description Background: Traditional measurements of vaccine coverage at specific ages can mask poor vaccine timeliness. However, optimal measurement of timing is unclear due to variations in countries’ recommended vaccination schedules and lack of a commonly accepted standard for “timeliness”. We conducted a systematic review of literature on vaccine timeliness and delay in low- and middle-income countries from 2007 to 2017. Methods: A search of articles published between January 1 2007 and December 31 2017, was performed in PubMed, EBSCOhost, and Embase. Results: 67 papers were included, of which 83% used a categorical measure of delay and 41% evaluated continuous delay. The most common age at assessment was 1 month, with earlier age benchmarks typically used with birth doses. Conclusions: Categorical definitions of vaccination timing vary widely, with benchmarks of delay varying from days to weeks to months. Use of a continuous measure of vaccine delay may be more informative and comparable.
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spelling doaj.art-2430c6c619ca4d89bc63a3bb4638c3762023-09-22T08:45:31ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2019-12-0115122790280510.1080/21645515.2019.16165031616503Vaccination timeliness and delay in low- and middle-income countries: a systematic review of the literature, 2007-2017Nina B. Masters0Abram L. Wagner1Matthew L. Boulton2School of Public Health, University of MichiganSchool of Public Health, University of MichiganSchool of Public Health, University of MichiganBackground: Traditional measurements of vaccine coverage at specific ages can mask poor vaccine timeliness. However, optimal measurement of timing is unclear due to variations in countries’ recommended vaccination schedules and lack of a commonly accepted standard for “timeliness”. We conducted a systematic review of literature on vaccine timeliness and delay in low- and middle-income countries from 2007 to 2017. Methods: A search of articles published between January 1 2007 and December 31 2017, was performed in PubMed, EBSCOhost, and Embase. Results: 67 papers were included, of which 83% used a categorical measure of delay and 41% evaluated continuous delay. The most common age at assessment was 1 month, with earlier age benchmarks typically used with birth doses. Conclusions: Categorical definitions of vaccination timing vary widely, with benchmarks of delay varying from days to weeks to months. Use of a continuous measure of vaccine delay may be more informative and comparable.http://dx.doi.org/10.1080/21645515.2019.1616503vaccine timelinessvaccine coverageexpanded program on immunization
spellingShingle Nina B. Masters
Abram L. Wagner
Matthew L. Boulton
Vaccination timeliness and delay in low- and middle-income countries: a systematic review of the literature, 2007-2017
Human Vaccines & Immunotherapeutics
vaccine timeliness
vaccine coverage
expanded program on immunization
title Vaccination timeliness and delay in low- and middle-income countries: a systematic review of the literature, 2007-2017
title_full Vaccination timeliness and delay in low- and middle-income countries: a systematic review of the literature, 2007-2017
title_fullStr Vaccination timeliness and delay in low- and middle-income countries: a systematic review of the literature, 2007-2017
title_full_unstemmed Vaccination timeliness and delay in low- and middle-income countries: a systematic review of the literature, 2007-2017
title_short Vaccination timeliness and delay in low- and middle-income countries: a systematic review of the literature, 2007-2017
title_sort vaccination timeliness and delay in low and middle income countries a systematic review of the literature 2007 2017
topic vaccine timeliness
vaccine coverage
expanded program on immunization
url http://dx.doi.org/10.1080/21645515.2019.1616503
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