A role for a novel natural antisense-BDNF in the maintenance of nicotine-seeking

A role for a novel natural antisense-BDNF in the maintenance of nicotine-seeking

Brain derived neurotrophic factor (BDNF) is critical for the extinction of drug-seeking. Expression of the Bdnf gene is highly epigenetically regulated, including via interactions with non-coding RNA. Here we investigate whether a long non-coding RNA antisense to Bdnf exon IV is involved in extincti...

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Bibliographic Details
Main Authors: Neil A. Youngson, Matthew R. Castino, Angela Stuart, Kelly A. Kershaw, Nathan M. Holmes, Eilish C. Heffernan, Paul D. Waters, Kevin V. Morris, Kelly J. Clemens
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Addiction Neuroscience
Subjects:
Infralimbic
Non-coding RNA
Addiction
Rat
Extinction
Antisense
Online Access:http://www.sciencedirect.com/science/article/pii/S2772392522000062

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