Multiple Myeloma with Intracranial Distribution
Multiple myeloma (MM) is a malignant immunoproliferative disease involving plasma cells, leading to their malignant proliferation and the production of monoclonal paraproteins. Intracranial tumor spread in MM is very rare. This is a unique and infrequent localization, which makes it difficult to dia...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Luchevaya Diagnostika, LLC
2023-06-01
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| Series: | Вестник рентгенологии и радиологии |
| Subjects: | |
| Online Access: | https://www.russianradiology.ru/jour/article/view/782 |
| _version_ | 1826587710170595328 |
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| author | A. Yu. Rynda О. А. Pavlov О. P. Verbitskiy D. А. Sitovskaya M. Yu. Podgornyak |
| author_facet | A. Yu. Rynda О. А. Pavlov О. P. Verbitskiy D. А. Sitovskaya M. Yu. Podgornyak |
| author_sort | A. Yu. Rynda |
| collection | DOAJ |
| description | Multiple myeloma (MM) is a malignant immunoproliferative disease involving plasma cells, leading to their malignant proliferation and the production of monoclonal paraproteins. Intracranial tumor spread in MM is very rare. This is a unique and infrequent localization, which makes it difficult to diagnose the disease. We report a rare case of treatment of a patient with MM intracranial spread, whose disease was presumably in remission and recurred as an intracranial plasmacytoma with a clinical picture of acute cerebrovascular accident. Surgical intervention was performed to remove the tumor, a histopathological analysis of the removed tissue was carried out. Even with early diagnosis, the prognosis remains bleak, with median survival rates of 3 to 6 months. However, aggressive multimodal treatment can prolong life by months. |
| first_indexed | 2024-03-08T10:21:23Z |
| format | Article |
| id | doaj.art-2439af3589554dc68fcaf47afbc756ea |
| institution | Directory Open Access Journal |
| issn | 0042-4676 2619-0478 |
| language | English |
| last_indexed | 2025-03-14T16:29:45Z |
| publishDate | 2023-06-01 |
| publisher | Luchevaya Diagnostika, LLC |
| record_format | Article |
| series | Вестник рентгенологии и радиологии |
| spelling | doaj.art-2439af3589554dc68fcaf47afbc756ea2025-02-21T12:05:30ZengLuchevaya Diagnostika, LLCВестник рентгенологии и радиологии0042-46762619-04782023-06-011041566110.20862/0042-4676-2023-104-1-56-61431Multiple Myeloma with Intracranial DistributionA. Yu. Rynda0О. А. Pavlov1О. P. Verbitskiy2D. А. Sitovskaya3M. Yu. Podgornyak4City Mariinsky HospitalCity Mariinsky HospitalCity Mariinsky HospitalCity Mariinsky HospitalCity Mariinsky HospitalMultiple myeloma (MM) is a malignant immunoproliferative disease involving plasma cells, leading to their malignant proliferation and the production of monoclonal paraproteins. Intracranial tumor spread in MM is very rare. This is a unique and infrequent localization, which makes it difficult to diagnose the disease. We report a rare case of treatment of a patient with MM intracranial spread, whose disease was presumably in remission and recurred as an intracranial plasmacytoma with a clinical picture of acute cerebrovascular accident. Surgical intervention was performed to remove the tumor, a histopathological analysis of the removed tissue was carried out. Even with early diagnosis, the prognosis remains bleak, with median survival rates of 3 to 6 months. However, aggressive multimodal treatment can prolong life by months.https://www.russianradiology.ru/jour/article/view/782multiple myelomasoft-tissue plasmacytomaextramedullary diseaseintracranial spreadneurooncology |
| spellingShingle | A. Yu. Rynda О. А. Pavlov О. P. Verbitskiy D. А. Sitovskaya M. Yu. Podgornyak Multiple Myeloma with Intracranial Distribution Вестник рентгенологии и радиологии multiple myeloma soft-tissue plasmacytoma extramedullary disease intracranial spread neurooncology |
| title | Multiple Myeloma with Intracranial Distribution |
| title_full | Multiple Myeloma with Intracranial Distribution |
| title_fullStr | Multiple Myeloma with Intracranial Distribution |
| title_full_unstemmed | Multiple Myeloma with Intracranial Distribution |
| title_short | Multiple Myeloma with Intracranial Distribution |
| title_sort | multiple myeloma with intracranial distribution |
| topic | multiple myeloma soft-tissue plasmacytoma extramedullary disease intracranial spread neurooncology |
| url | https://www.russianradiology.ru/jour/article/view/782 |
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