A Subunit Vaccine Candidate Composed of Mpox Virus A29L, M1R, A35R, and B6R Elicits Robust Immune Response in Mice

A Subunit Vaccine Candidate Composed of Mpox Virus A29L, M1R, A35R, and B6R Elicits Robust Immune Response in Mice

With no specific antiviral drugs and preventive vaccines against Mpox virus (MPXV), the epidemic has led to the declaration of a Public Health Emergency of International Concern. As a developmental direction for new vaccines, studies of subunit vaccines based upon MPXV antigen proteins are lacking....

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Bibliographic Details
Main Authors: Xuetao Yang, Xidan Yang, Shouwen Du, Congxia Hu, Xiu Yang, Xingyun Wang, Xing Hu, Nino Rcheulishvili, Peng George Wang, Jihui Lin
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Vaccines
Subjects:
Mpox virus
subunit vaccine
CpG7909 adjuvant
prokaryotic expression
immune response
Online Access:https://www.mdpi.com/2076-393X/11/9/1420

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