Radiation therapy techniques in the treatment of skin cancer: an overview of the current status and outlook

Nonmelanoma skin cancer (NMSC) is a major health concern due to its high incidence rate, its negative impact on the quality of life of patients as well as the associated economic burden to the healthcare system. Surgery is currently the primary treatment offered for skin cancer patients but not appl...

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Main Authors: Ali Pashazadeh, Axel Boese, Michael Friebe
Format: Article
Language:English
Published: Taylor & Francis Group 2019-11-01
Series:Journal of Dermatological Treatment
Subjects:
Online Access:http://dx.doi.org/10.1080/09546634.2019.1573310
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author Ali Pashazadeh
Axel Boese
Michael Friebe
author_facet Ali Pashazadeh
Axel Boese
Michael Friebe
author_sort Ali Pashazadeh
collection DOAJ
description Nonmelanoma skin cancer (NMSC) is a major health concern due to its high incidence rate, its negative impact on the quality of life of patients as well as the associated economic burden to the healthcare system. Surgery is currently the primary treatment offered for skin cancer patients but not applicable or available in all cases. Radiation therapy (RT), with its long successful history in the management of cancer, has shown to be an effective alternative or complementary method in cutaneous oncology. Specifically, for dermatology applications, RT is very often the preferred option due to its favorable cosmetic results, besides the excellent control rate of the tumor. During the last 120 years since the introduction of treatments based on ionizing radiation, several techniques in this area have been developed. Radionuclide brachytherapy, electronic brachytherapy, X-ray therapies with kilovolt (kV) to megavolt (MV) photons and electron beam therapy are the established methods that are currently used on skin cancer patients. The purpose of this article is to overview these techniques and discuss the pros and cons of these methods in dermatology practices. Additionally, a new approach of beta RT of superficial skin tumors is discussed, which may offer exciting features in the management of NMSC.
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spelling doaj.art-2440315c58034de3b8c4a302e7fd25772023-09-15T14:08:34ZengTaylor & Francis GroupJournal of Dermatological Treatment0954-66341471-17532019-11-0130883183910.1080/09546634.2019.15733101573310Radiation therapy techniques in the treatment of skin cancer: an overview of the current status and outlookAli Pashazadeh0Axel Boese1Michael Friebe2Otto von Guericke UniversityOtto von Guericke UniversityOtto von Guericke UniversityNonmelanoma skin cancer (NMSC) is a major health concern due to its high incidence rate, its negative impact on the quality of life of patients as well as the associated economic burden to the healthcare system. Surgery is currently the primary treatment offered for skin cancer patients but not applicable or available in all cases. Radiation therapy (RT), with its long successful history in the management of cancer, has shown to be an effective alternative or complementary method in cutaneous oncology. Specifically, for dermatology applications, RT is very often the preferred option due to its favorable cosmetic results, besides the excellent control rate of the tumor. During the last 120 years since the introduction of treatments based on ionizing radiation, several techniques in this area have been developed. Radionuclide brachytherapy, electronic brachytherapy, X-ray therapies with kilovolt (kV) to megavolt (MV) photons and electron beam therapy are the established methods that are currently used on skin cancer patients. The purpose of this article is to overview these techniques and discuss the pros and cons of these methods in dermatology practices. Additionally, a new approach of beta RT of superficial skin tumors is discussed, which may offer exciting features in the management of NMSC.http://dx.doi.org/10.1080/09546634.2019.1573310skin cancerradiation therapyradionuclide brachytherapyelectronic brachytherapyelectron beam therapybeta particles
spellingShingle Ali Pashazadeh
Axel Boese
Michael Friebe
Radiation therapy techniques in the treatment of skin cancer: an overview of the current status and outlook
Journal of Dermatological Treatment
skin cancer
radiation therapy
radionuclide brachytherapy
electronic brachytherapy
electron beam therapy
beta particles
title Radiation therapy techniques in the treatment of skin cancer: an overview of the current status and outlook
title_full Radiation therapy techniques in the treatment of skin cancer: an overview of the current status and outlook
title_fullStr Radiation therapy techniques in the treatment of skin cancer: an overview of the current status and outlook
title_full_unstemmed Radiation therapy techniques in the treatment of skin cancer: an overview of the current status and outlook
title_short Radiation therapy techniques in the treatment of skin cancer: an overview of the current status and outlook
title_sort radiation therapy techniques in the treatment of skin cancer an overview of the current status and outlook
topic skin cancer
radiation therapy
radionuclide brachytherapy
electronic brachytherapy
electron beam therapy
beta particles
url http://dx.doi.org/10.1080/09546634.2019.1573310
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AT axelboese radiationtherapytechniquesinthetreatmentofskincanceranoverviewofthecurrentstatusandoutlook
AT michaelfriebe radiationtherapytechniquesinthetreatmentofskincanceranoverviewofthecurrentstatusandoutlook