The Role of Cluster of Differentiation 39 (CD39) and Purinergic Signaling Pathway in Viral Infections
CD39 is a marker of immune cells such as lymphocytes and monocytes. The CD39/CD73 pathway hydrolyzes ATP into adenosine, which has a potent immunosuppressive effect. CD39 regulates the function of a variety of immunologic cells through the purinergic signaling pathways. CD39+ T cells have been impli...
Main Authors: | Alaa Elsaghir, Ehsan M. W. El-Sabaa, Abdulrahman K. Ahmed, Sayed F. Abdelwahab, Ibrahim M. Sayed, Mohamed A. El-Mokhtar |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-02-01
|
Series: | Pathogens |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-0817/12/2/279 |
Similar Items
-
The role of ectonucleotidases CD39 and CD73 and adenosine signalling in solid organ transplantation
by: Veena eRoberts, et al.
Published: (2014-02-01) -
PURINERGIC REGULATION OF BASIC PHYSIOLOGICAL AND PATHOLOGICAL PROCESSES
by: A. S. Golovkin, et al.
Published: (2018-06-01) -
Decreased Frequency of Intestinal CD39+ γδ+ T Cells With Tissue-Resident Memory Phenotype in Inflammatory Bowel Disease
by: Jana Libera, et al.
Published: (2020-09-01) -
What Else Can CD39 Tell Us?
by: Hai Zhao, et al.
Published: (2017-06-01) -
Antisense oligonucleotide targeting CD39 improves anti-tumor T cell immunity
by: Abhishek S. Kashyap, et al.
Published: (2019-03-01)