Small extracellular vesicles: multi-faceted tools for leukemia immune evasion in vivo

Small extracellular vesicles: multi-faceted tools for leukemia immune evasion in vivo

Recently, small extracellular vesicles (sEVs) secreted in vivo from chronic lymphocytic leukemia (CLL) preclinical murine models were characterized. Leukemia microenvironment sEV (LME-sEVs) selectively target CD8+ T-cells, inducing exhaustion and hampering anti-tumor immune response. Additionally, a...

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Bibliographic Details
Main Authors:	Ernesto Gargiulo, Elodie Viry, Etienne Moussay, Jerome Paggetti
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2022-12-01
Series:	OncoImmunology
Subjects:	Small extracellular vesicles exosomes CLL tumor microenvironment tumor immune escape sEV-based biomarkers
Online Access:	https://www.tandfonline.com/doi/10.1080/2162402X.2022.2127507

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