High Affinity, Developability and Functional Size: The Holy Grail of Combinatorial Antibody Library Generation

High Affinity, Developability and Functional Size: The Holy Grail of Combinatorial Antibody Library Generation

Since the initial description of phage display technology for the generation of human antibodies, a variety of selection methods has been developed. The most critical parameter for all in vitro-based approaches is the quality of the antibody library. Concurrent evolution of the libraries has allowed...

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Bibliographic Details
Main Authors: Kathrin Tissot, Julia Neugebauer, Dirk Ponsel, Kathrin Ladetzki-Baehs
Format: Article
Language:English
Published: MDPI AG 2011-05-01
Series:Molecules
Subjects:
phage display
library
Online Access:http://www.mdpi.com/1420-3049/16/5/3675/

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