Influence of the CXCL1 rs4074 A allele on alcohol induced cirrhosis and HCC in patients of European descent.

Influence of the CXCL1 rs4074 A allele on alcohol induced cirrhosis and HCC in patients of European descent.

<h4>Background and aims</h4>CXCL1 (CXC chemokine-ligand-1) is a ligand for CXC chemokine receptor 2 expressed on hepatic stellate cells (HSC). Thus, CXCL1 might contribute to HSC activation and fibrogenesis. In the present study, we investigated the influence of the CXCL1 rs4074 polymorp...

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Main Authors: Hans Dieter Nischalke, Cordula Berger, Philipp Lutz, Bettina Langhans, Franziska Wolter, Marianne Eisenhardt, Benjamin Krämer, Pavlos Kokordelis, Andreas Glässner, Tobias Müller, Jonas Rosendahl, Janett Fischer, Thomas Berg, Frank Grünhage, Ludger Leifeld, Michael Soyka, Jacob Nattermann, Tilman Sauerbruch, Felix Stickel, Ulrich Spengler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24260493/?tool=EBI

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