Repurposing of Miltefosine as an Adjuvant for Influenza Vaccine

Repurposing of Miltefosine as an Adjuvant for Influenza Vaccine

We previously reported that topical imiquimod can improve the immunogenicity of the influenza vaccine. This study investigated another FDA-approved drug, miltefosine (MTF), as a vaccine adjuvant. Mice immunized with an influenza vaccine with or without MTF adjuvant were challenged by a lethal dose o...

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Bibliographic Details
Main Authors: Lu Lu, Carol Ho-Yan Fong, Anna Jinxia Zhang, Wai-Lan Wu, Iris Can Li, Andrew Chak-Yiu Lee, Thrimendra Kaushika Dissanayake, Linlei Chen, Ivan Fan-Ngai Hung, Kwok-Hung Chan, Hin Chu, Kin-Hang Kok, Kwok-Yung Yuen, Kelvin Kai-Wang To
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Vaccines
Subjects:
influenza vaccine
vaccine
adjuvant
T<sub>FH</sub>
miltefosine
Online Access:https://www.mdpi.com/2076-393X/8/4/754

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