Khalid G. Al-Fartosi Tannic acid(TA) protects against cadmium acetate induced toxicity in female rats (Role of tannic acid AS antioxidant)

Cadmium is a highly toxic element that can be ingested or inhaled from a variety of industrial and dietary sources. Tannic acid (TA) is a plant polyphenol found in many dietary plant materials such as grain sorghum, coffee, tea and cocoa. The purpose of this study was to investigate the role of tan...

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Main Author: Khalid Al-Fartosi
Format: Article
Language:English
Published: University of Thi-Qar 2019-05-01
Series:مجلة علوم ذي قار
Subjects:
Online Access:https://www.jsci.utq.edu.iq/index.php/main/article/view/335
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author Khalid Al-Fartosi
author_facet Khalid Al-Fartosi
author_sort Khalid Al-Fartosi
collection DOAJ
description Cadmium is a highly toxic element that can be ingested or inhaled from a variety of industrial and dietary sources. Tannic acid (TA) is a plant polyphenol found in many dietary plant materials such as grain sorghum, coffee, tea and cocoa. The purpose of this study was to investigate the role of tannic acid against cadmium acetate induced toxicity in female rats.Three  groups of adult female rats were treated orally with normal saline (0.09 Nacl) as a control group, 200 ppm cadmium acetate (first treated group), and 200 ppm + 200 ppm tannic acid (second treated group) for 12 weeks. The results indicated that cadmium acetate caused a significant decreased in RBCs count, Hb concentration, and PCV of female rats compared with control group, while that tannic acid enhanced these parameters. Also, the results showed that cadmium acetate induced a significant alternative in total and differential count of WBC, while these changes were attenuated by the tannic acid administration. Total protein and albumin were decreased significantly in female rats treated with cadmium, while there was non significant differences between these parameters in control female rats compared with Cd + TA treated rats. AST, ALT, ALP, Cholesterol, and TG were increased significantly in cadmium treated rats, but these values were decreased according to (TA) administration.
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spelling doaj.art-244588bd579b427089af0facf9da08572023-11-18T09:29:27ZengUniversity of Thi-Qarمجلة علوم ذي قار1991-86902709-02562019-05-0122Khalid G. Al-Fartosi Tannic acid(TA) protects against cadmium acetate induced toxicity in female rats (Role of tannic acid AS antioxidant) Khalid Al-Fartosi Cadmium is a highly toxic element that can be ingested or inhaled from a variety of industrial and dietary sources. Tannic acid (TA) is a plant polyphenol found in many dietary plant materials such as grain sorghum, coffee, tea and cocoa. The purpose of this study was to investigate the role of tannic acid against cadmium acetate induced toxicity in female rats.Three  groups of adult female rats were treated orally with normal saline (0.09 Nacl) as a control group, 200 ppm cadmium acetate (first treated group), and 200 ppm + 200 ppm tannic acid (second treated group) for 12 weeks. The results indicated that cadmium acetate caused a significant decreased in RBCs count, Hb concentration, and PCV of female rats compared with control group, while that tannic acid enhanced these parameters. Also, the results showed that cadmium acetate induced a significant alternative in total and differential count of WBC, while these changes were attenuated by the tannic acid administration. Total protein and albumin were decreased significantly in female rats treated with cadmium, while there was non significant differences between these parameters in control female rats compared with Cd + TA treated rats. AST, ALT, ALP, Cholesterol, and TG were increased significantly in cadmium treated rats, but these values were decreased according to (TA) administration. https://www.jsci.utq.edu.iq/index.php/main/article/view/335Cadmium, Tannic acid, Female rats
spellingShingle Khalid Al-Fartosi
Khalid G. Al-Fartosi Tannic acid(TA) protects against cadmium acetate induced toxicity in female rats (Role of tannic acid AS antioxidant)
مجلة علوم ذي قار
Cadmium, Tannic acid, Female rats
title Khalid G. Al-Fartosi Tannic acid(TA) protects against cadmium acetate induced toxicity in female rats (Role of tannic acid AS antioxidant)
title_full Khalid G. Al-Fartosi Tannic acid(TA) protects against cadmium acetate induced toxicity in female rats (Role of tannic acid AS antioxidant)
title_fullStr Khalid G. Al-Fartosi Tannic acid(TA) protects against cadmium acetate induced toxicity in female rats (Role of tannic acid AS antioxidant)
title_full_unstemmed Khalid G. Al-Fartosi Tannic acid(TA) protects against cadmium acetate induced toxicity in female rats (Role of tannic acid AS antioxidant)
title_short Khalid G. Al-Fartosi Tannic acid(TA) protects against cadmium acetate induced toxicity in female rats (Role of tannic acid AS antioxidant)
title_sort khalid g al fartosi tannic acid ta protects against cadmium acetate induced toxicity in female rats role of tannic acid as antioxidant
topic Cadmium, Tannic acid, Female rats
url https://www.jsci.utq.edu.iq/index.php/main/article/view/335
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