H-index is important for postural control for people with impaired foot sole sensation.
<h4>Introduction</h4>People with Peripheral Neuropathy (PN), especially those with impaired sensory inputs through the small-afferent fiber (type II afferent fibers) reflex loop (SAF), might depend more on the large-afferent fiber (type I afferent fibers) reflex loop (LAF) for postural c...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2015-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0121847 |
| _version_ | 1818359671210115072 |
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| author | Shuqi Zhang Brad Manor Li Li |
| author_facet | Shuqi Zhang Brad Manor Li Li |
| author_sort | Shuqi Zhang |
| collection | DOAJ |
| description | <h4>Introduction</h4>People with Peripheral Neuropathy (PN), especially those with impaired sensory inputs through the small-afferent fiber (type II afferent fibers) reflex loop (SAF), might depend more on the large-afferent fiber (type I afferent fibers) reflex loop (LAF) for postural control.<h4>Purpose</h4>To examine whether the function of the LAF reflex loop, reflected by the H-reflex and ankle joint proprioception, influences postural control when the SAF reflex loop is impaired, as indicated by reduced foot sole cutaneous sensation.<h4>Methods</h4>Thirteen participants (8 women, 5 men) diagnosed with PN and 12 age-matched controls (7 women, 5 men) completed the testing protocol. Measures of interest included the H-index, active (AAP) and passive (PAP) ankle proprioception, plantar pressure sensitivity (PPS), average sway velocity (VAVG) and area (A95) during 30 seconds eyes-closed standing, 6-minute walk distance (6MWD) and timed up-and-go duration (TUG).<h4>Results</h4>Statistically significant group-dependent regression was observed between VAVG and H-index. Compared to the control group, the PN group demonstrated reduced PPS (2.0 ± 1.9 vs. 4.2 ± 1.2, P < .05) and H-index (63.6 ± 10.9 vs. 76.4 ± 16.0, P < .05), greater VAVG (3.5 ± 2.1 vs. 1.6 ± 0.6 cm/s, P < .05) and A95 (10.0 ± 10.1 vs. 2.5 ± 1.5 cm2, P < .05), shorter 6MWD (442.2 ± 93.0 vs. 525.3 ± 68.2 m, P < .05), and longer TUG (9.4 ± 1.6 vs. 6.5 ± 1.3 s, P < .05). Within the PN group, but not the control group, the H-index was correlated with VAVG (r = -.56, P < .05). Moreover, within the PN group only, PAP scores were correlated with 6MWD (r = -.68, P < .05) and TUG (r = -.59, P < .05) performance. No other statistically significant group difference, correlation or group-dependent regression was observed.<h4>Conclusion</h4>VAVG, 6MWD, and TUG correlated with LAF reflex loop function observed among those with impaired functioning of the SAF reflex loop. This observation suggests that the LAF reflex loop may be critical to the control of balance in those individuals suffering from small-fiber PN. |
| first_indexed | 2024-12-13T20:48:36Z |
| format | Article |
| id | doaj.art-2447f59bd35c45adbf0a680fcb28760c |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-13T20:48:36Z |
| publishDate | 2015-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-2447f59bd35c45adbf0a680fcb28760c2022-12-21T23:31:56ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-01103e012184710.1371/journal.pone.0121847H-index is important for postural control for people with impaired foot sole sensation.Shuqi ZhangBrad ManorLi Li<h4>Introduction</h4>People with Peripheral Neuropathy (PN), especially those with impaired sensory inputs through the small-afferent fiber (type II afferent fibers) reflex loop (SAF), might depend more on the large-afferent fiber (type I afferent fibers) reflex loop (LAF) for postural control.<h4>Purpose</h4>To examine whether the function of the LAF reflex loop, reflected by the H-reflex and ankle joint proprioception, influences postural control when the SAF reflex loop is impaired, as indicated by reduced foot sole cutaneous sensation.<h4>Methods</h4>Thirteen participants (8 women, 5 men) diagnosed with PN and 12 age-matched controls (7 women, 5 men) completed the testing protocol. Measures of interest included the H-index, active (AAP) and passive (PAP) ankle proprioception, plantar pressure sensitivity (PPS), average sway velocity (VAVG) and area (A95) during 30 seconds eyes-closed standing, 6-minute walk distance (6MWD) and timed up-and-go duration (TUG).<h4>Results</h4>Statistically significant group-dependent regression was observed between VAVG and H-index. Compared to the control group, the PN group demonstrated reduced PPS (2.0 ± 1.9 vs. 4.2 ± 1.2, P < .05) and H-index (63.6 ± 10.9 vs. 76.4 ± 16.0, P < .05), greater VAVG (3.5 ± 2.1 vs. 1.6 ± 0.6 cm/s, P < .05) and A95 (10.0 ± 10.1 vs. 2.5 ± 1.5 cm2, P < .05), shorter 6MWD (442.2 ± 93.0 vs. 525.3 ± 68.2 m, P < .05), and longer TUG (9.4 ± 1.6 vs. 6.5 ± 1.3 s, P < .05). Within the PN group, but not the control group, the H-index was correlated with VAVG (r = -.56, P < .05). Moreover, within the PN group only, PAP scores were correlated with 6MWD (r = -.68, P < .05) and TUG (r = -.59, P < .05) performance. No other statistically significant group difference, correlation or group-dependent regression was observed.<h4>Conclusion</h4>VAVG, 6MWD, and TUG correlated with LAF reflex loop function observed among those with impaired functioning of the SAF reflex loop. This observation suggests that the LAF reflex loop may be critical to the control of balance in those individuals suffering from small-fiber PN.https://doi.org/10.1371/journal.pone.0121847 |
| spellingShingle | Shuqi Zhang Brad Manor Li Li H-index is important for postural control for people with impaired foot sole sensation. PLoS ONE |
| title | H-index is important for postural control for people with impaired foot sole sensation. |
| title_full | H-index is important for postural control for people with impaired foot sole sensation. |
| title_fullStr | H-index is important for postural control for people with impaired foot sole sensation. |
| title_full_unstemmed | H-index is important for postural control for people with impaired foot sole sensation. |
| title_short | H-index is important for postural control for people with impaired foot sole sensation. |
| title_sort | h index is important for postural control for people with impaired foot sole sensation |
| url | https://doi.org/10.1371/journal.pone.0121847 |
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