Gene expression of cytokines and prostaglandin metabolism–related proteins in eosinophilic otitis media

Gene expression of cytokines and prostaglandin metabolism–related proteins in eosinophilic otitis media

The objective of this study was to investigate the levels of gene expression in the middle ear mucosa of 2 patients diagnosed with eosinophilic otitis media. One patient with severe hearing loss showed high expression levels of genes encoding IL-5 and IL-33 receptors.

Bibliographic Details
Main Authors: Aiko Oka, MD, Masahiro Takahashi, MD, Wataru Nishimura, MD, PhD, Shogo Oyamada, MD, Shinichiro Oka, MD, Satoshi Iwasaki, MD, Kengo Kanai, MD, Mitsuhiro Okano, MD
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Journal of Allergy and Clinical Immunology: Global
Subjects:
Eosinophilic otitis media
type 2 inflammation
gene expression
severity
pathogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S277282932400033X

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