A prognosis and cost-effectiveness systematic review of non-invasive treatments for root caries

Aim: to evaluate the prognosis of root caries treatment with non-invasive methods, as well as to compare non-invasive therapies as viable alternatives for clinicians, indicating their cost-effectiveness. Literature review: Data collected were number of active lesions at baseline(BL) and in the last...

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Main Authors: Fábio Luiz de Resende Cussi, Déborah Lousan do Nascimento Poubel, Adriano de Almeida de Lima, Ana Claudia Morais Godoy Figueiredo, Cristine Miron Stefani, Fernanda Cristina Pimentel Garcia, Nailê Damé-Teixeira
Format: Article
Language:English
Published: Universidade Federal do Rio Grande do Sul. Faculdade de Odontologia 2023-07-01
Series:Revista da Faculdade de Odontologia de Porto Alegre
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Online Access:https://seer.ufrgs.br/index.php/RevistadaFaculdadeOdontologia/article/view/130357
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author Fábio Luiz de Resende Cussi
Déborah Lousan do Nascimento Poubel
Adriano de Almeida de Lima
Ana Claudia Morais Godoy Figueiredo
Cristine Miron Stefani
Fernanda Cristina Pimentel Garcia
Nailê Damé-Teixeira
author_facet Fábio Luiz de Resende Cussi
Déborah Lousan do Nascimento Poubel
Adriano de Almeida de Lima
Ana Claudia Morais Godoy Figueiredo
Cristine Miron Stefani
Fernanda Cristina Pimentel Garcia
Nailê Damé-Teixeira
author_sort Fábio Luiz de Resende Cussi
collection DOAJ
description Aim: to evaluate the prognosis of root caries treatment with non-invasive methods, as well as to compare non-invasive therapies as viable alternatives for clinicians, indicating their cost-effectiveness. Literature review: Data collected were number of active lesions at baseline(BL) and in the last clinical assessment after follow-up(FL), and the follow-up period in months(P). The outcome was the monthly progression rate of the lesions that was calculated by (FL–BL)/P. A negative progression rate means the arrestment of the lesions. A cost-effectiveness rate was calculated. Results: From 596 titles retrieved in the search, 8 studies were included in a qualitative synthesis after assessed for eligibility. The monthly progression rate of lesions of home-based treatments (toothpastes, mouth rinses, supplemented milk intake) was an average of -0.79 (-3.68 to 2.3), while the office-based treatments (varnish, topic solutions) was 0.07 (-0.01 to 0.51), suggesting a better prognosis of the home-based treatments. The lowest monthly progression rate was -3.97 (toothpaste 5000ppm/F) while the highest was 2.31 (conventional toothpaste). The cost-effectiveness rate was better for treatments with toothpastes with 5000ppm/F (BRL21.78) when compared to mouthwashes (BRL579.47). Discussion: A better prognosis was found for toothpastes with a high fluoride concentration (5000ppm/F) compared to other therapies, as well as a better cost-effectiveness when compared to mouthwashes. Conclusion: Home-based therapies represented the highest rates of good prognosis for treating root caries lesions within the available scientific evidence. Although 5000ppm/F toothpastes have a very high cost for the Brazilian market, this treatment presented the highest cost-effectiveness when compared to mouthrinses (PROSPERO:CRD42019136035).
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spelling doaj.art-2452e8b333284a1bba9f42cfbcb20dba2024-02-15T19:41:16ZengUniversidade Federal do Rio Grande do Sul. Faculdade de OdontologiaRevista da Faculdade de Odontologia de Porto Alegre0566-18542177-00182023-07-0164e130357e13035710.22456/2177-0018.130357110397A prognosis and cost-effectiveness systematic review of non-invasive treatments for root cariesFábio Luiz de Resende Cussihttps://orcid.org/0000-0001-9747-8753Déborah Lousan do Nascimento Poubelhttps://orcid.org/0000-0002-7560-7320Adriano de Almeida de Limahttps://orcid.org/0000-0002-4125-6980Ana Claudia Morais Godoy FigueiredoCristine Miron Stefanihttps://orcid.org/0000-0003-4712-9779Fernanda Cristina Pimentel Garciahttps://orcid.org/0000-0002-3709-1212Nailê Damé-Teixeirahttps://orcid.org/0000-0002-0490-0036Aim: to evaluate the prognosis of root caries treatment with non-invasive methods, as well as to compare non-invasive therapies as viable alternatives for clinicians, indicating their cost-effectiveness. Literature review: Data collected were number of active lesions at baseline(BL) and in the last clinical assessment after follow-up(FL), and the follow-up period in months(P). The outcome was the monthly progression rate of the lesions that was calculated by (FL–BL)/P. A negative progression rate means the arrestment of the lesions. A cost-effectiveness rate was calculated. Results: From 596 titles retrieved in the search, 8 studies were included in a qualitative synthesis after assessed for eligibility. The monthly progression rate of lesions of home-based treatments (toothpastes, mouth rinses, supplemented milk intake) was an average of -0.79 (-3.68 to 2.3), while the office-based treatments (varnish, topic solutions) was 0.07 (-0.01 to 0.51), suggesting a better prognosis of the home-based treatments. The lowest monthly progression rate was -3.97 (toothpaste 5000ppm/F) while the highest was 2.31 (conventional toothpaste). The cost-effectiveness rate was better for treatments with toothpastes with 5000ppm/F (BRL21.78) when compared to mouthwashes (BRL579.47). Discussion: A better prognosis was found for toothpastes with a high fluoride concentration (5000ppm/F) compared to other therapies, as well as a better cost-effectiveness when compared to mouthwashes. Conclusion: Home-based therapies represented the highest rates of good prognosis for treating root caries lesions within the available scientific evidence. Although 5000ppm/F toothpastes have a very high cost for the Brazilian market, this treatment presented the highest cost-effectiveness when compared to mouthrinses (PROSPERO:CRD42019136035).https://seer.ufrgs.br/index.php/RevistadaFaculdadeOdontologia/article/view/130357root cariesfluorides, topicalcost-benefit analysis
spellingShingle Fábio Luiz de Resende Cussi
Déborah Lousan do Nascimento Poubel
Adriano de Almeida de Lima
Ana Claudia Morais Godoy Figueiredo
Cristine Miron Stefani
Fernanda Cristina Pimentel Garcia
Nailê Damé-Teixeira
A prognosis and cost-effectiveness systematic review of non-invasive treatments for root caries
Revista da Faculdade de Odontologia de Porto Alegre
root caries
fluorides, topical
cost-benefit analysis
title A prognosis and cost-effectiveness systematic review of non-invasive treatments for root caries
title_full A prognosis and cost-effectiveness systematic review of non-invasive treatments for root caries
title_fullStr A prognosis and cost-effectiveness systematic review of non-invasive treatments for root caries
title_full_unstemmed A prognosis and cost-effectiveness systematic review of non-invasive treatments for root caries
title_short A prognosis and cost-effectiveness systematic review of non-invasive treatments for root caries
title_sort prognosis and cost effectiveness systematic review of non invasive treatments for root caries
topic root caries
fluorides, topical
cost-benefit analysis
url https://seer.ufrgs.br/index.php/RevistadaFaculdadeOdontologia/article/view/130357
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