Effect of 8-Week Aquatic Training and Resistance Training on Plasma NT-4 Levels and NT-4 Expression in Peripheral Blood Mononuclear Cells in Women with Multiple Sclerosis
ABSTRACT Background and Objectives: The present study aimed to investigate effects of eight weeks of aquatic exercise and resistance training on plasma neurotrophin-4 (NT-4) levels and NT-4 expression in peripheral blood mononuclear cells (PBMCs) of women with multiple sclerosis (MS). ...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Golestan University of Medical Sciences
2017-11-01
|
| Series: | Medical Laboratory Journal |
| Subjects: | |
| Online Access: | http://mlj.goums.ac.ir/article-1-1019-en.html |
| _version_ | 1818157458769575936 |
|---|---|
| author | Asra Askari Amir Rashid Lamir Nahid Bijeh Majid Momeni Moghadam |
| author_facet | Asra Askari Amir Rashid Lamir Nahid Bijeh Majid Momeni Moghadam |
| author_sort | Asra Askari |
| collection | DOAJ |
| description | ABSTRACT
Background and Objectives: The present study aimed to investigate effects of eight weeks of aquatic exercise and resistance training on plasma neurotrophin-4 (NT-4) levels and NT-4 expression in peripheral blood mononuclear cells (PBMCs) of women with multiple sclerosis (MS).
Methods: Thirty women with MS were randomly assigned to a resistance-training group, an aquatic exercise group and a control group. After separating plasma and PBMCs from blood samples, level of plasma NT-4 and NT-4 expression was measured after eight weeks of exercise via ELISA and Real-time PCR, respectively.
Results: The level of plasma NT-4 and NT-4 expression increased significantly following eight weeks of aquatic training and resistance training.
Conclusion: Based on the results of the present study, both resistance training and aquatic exercise can increase the level of plasma NT-4 and NT-4 expression in female MS patients. It can be concluded that such trainings could have protective and positive effects on the nervous system of MS patients.
Keywords: Exercise, Multiple Sclerosis, Neurotrophic Factors, Women. |
| first_indexed | 2024-12-11T15:14:31Z |
| format | Article |
| id | doaj.art-24579eab2b03483ca4357aa0ed3424aa |
| institution | Directory Open Access Journal |
| issn | 2538-4449 |
| language | English |
| last_indexed | 2024-12-11T15:14:31Z |
| publishDate | 2017-11-01 |
| publisher | Golestan University of Medical Sciences |
| record_format | Article |
| series | Medical Laboratory Journal |
| spelling | doaj.art-24579eab2b03483ca4357aa0ed3424aa2022-12-22T01:00:37ZengGolestan University of Medical SciencesMedical Laboratory Journal2538-44492017-11-0111616Effect of 8-Week Aquatic Training and Resistance Training on Plasma NT-4 Levels and NT-4 Expression in Peripheral Blood Mononuclear Cells in Women with Multiple SclerosisAsra Askari0Amir Rashid Lamir1Nahid Bijeh2Majid Momeni Moghadam3 Department of Sport Physiology, Faculty of Physical Education and Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran Department of Sport Physiology, Faculty of Physical Education and Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran Department of Sport Physiology, Faculty of Physical Education and Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran Department of Biology, Faculty of Basic Sciences, Hakim Sabzevari University, Sabzevar, Iran ABSTRACT Background and Objectives: The present study aimed to investigate effects of eight weeks of aquatic exercise and resistance training on plasma neurotrophin-4 (NT-4) levels and NT-4 expression in peripheral blood mononuclear cells (PBMCs) of women with multiple sclerosis (MS). Methods: Thirty women with MS were randomly assigned to a resistance-training group, an aquatic exercise group and a control group. After separating plasma and PBMCs from blood samples, level of plasma NT-4 and NT-4 expression was measured after eight weeks of exercise via ELISA and Real-time PCR, respectively. Results: The level of plasma NT-4 and NT-4 expression increased significantly following eight weeks of aquatic training and resistance training. Conclusion: Based on the results of the present study, both resistance training and aquatic exercise can increase the level of plasma NT-4 and NT-4 expression in female MS patients. It can be concluded that such trainings could have protective and positive effects on the nervous system of MS patients. Keywords: Exercise, Multiple Sclerosis, Neurotrophic Factors, Women.http://mlj.goums.ac.ir/article-1-1019-en.htmlexercisemultiple sclerosisneurotrophic factorswomen. |
| spellingShingle | Asra Askari Amir Rashid Lamir Nahid Bijeh Majid Momeni Moghadam Effect of 8-Week Aquatic Training and Resistance Training on Plasma NT-4 Levels and NT-4 Expression in Peripheral Blood Mononuclear Cells in Women with Multiple Sclerosis Medical Laboratory Journal exercise multiple sclerosis neurotrophic factors women. |
| title | Effect of 8-Week Aquatic Training and Resistance Training on Plasma NT-4 Levels and NT-4 Expression in Peripheral Blood Mononuclear Cells in Women with Multiple Sclerosis |
| title_full | Effect of 8-Week Aquatic Training and Resistance Training on Plasma NT-4 Levels and NT-4 Expression in Peripheral Blood Mononuclear Cells in Women with Multiple Sclerosis |
| title_fullStr | Effect of 8-Week Aquatic Training and Resistance Training on Plasma NT-4 Levels and NT-4 Expression in Peripheral Blood Mononuclear Cells in Women with Multiple Sclerosis |
| title_full_unstemmed | Effect of 8-Week Aquatic Training and Resistance Training on Plasma NT-4 Levels and NT-4 Expression in Peripheral Blood Mononuclear Cells in Women with Multiple Sclerosis |
| title_short | Effect of 8-Week Aquatic Training and Resistance Training on Plasma NT-4 Levels and NT-4 Expression in Peripheral Blood Mononuclear Cells in Women with Multiple Sclerosis |
| title_sort | effect of 8 week aquatic training and resistance training on plasma nt 4 levels and nt 4 expression in peripheral blood mononuclear cells in women with multiple sclerosis |
| topic | exercise multiple sclerosis neurotrophic factors women. |
| url | http://mlj.goums.ac.ir/article-1-1019-en.html |
| work_keys_str_mv | AT asraaskari effectof8weekaquatictrainingandresistancetrainingonplasmant4levelsandnt4expressioninperipheralbloodmononuclearcellsinwomenwithmultiplesclerosis AT amirrashidlamir effectof8weekaquatictrainingandresistancetrainingonplasmant4levelsandnt4expressioninperipheralbloodmononuclearcellsinwomenwithmultiplesclerosis AT nahidbijeh effectof8weekaquatictrainingandresistancetrainingonplasmant4levelsandnt4expressioninperipheralbloodmononuclearcellsinwomenwithmultiplesclerosis AT majidmomenimoghadam effectof8weekaquatictrainingandresistancetrainingonplasmant4levelsandnt4expressioninperipheralbloodmononuclearcellsinwomenwithmultiplesclerosis |