Imaging Review of the Lung Parenchymal Complications in Patients with IPF

Idiopathic pulmonary fibrosis (IPF) is a chronic, pulmonary-limited, interstitial lung disease with a poor prognosis. This condition is characterized by different clinical scenarios, ranging from the most typical slow and progressive deterioration of symptoms to a rapid and abrupt decline of lung fu...

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Main Authors: Elisa Baratella, Ilaria Fiorese, Cristina Marrocchio, Francesco Salton, Maria Assunta Cova
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1010-660X/55/10/613
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author Elisa Baratella
Ilaria Fiorese
Cristina Marrocchio
Francesco Salton
Maria Assunta Cova
author_facet Elisa Baratella
Ilaria Fiorese
Cristina Marrocchio
Francesco Salton
Maria Assunta Cova
author_sort Elisa Baratella
collection DOAJ
description Idiopathic pulmonary fibrosis (IPF) is a chronic, pulmonary-limited, interstitial lung disease with a poor prognosis. This condition is characterized by different clinical scenarios, ranging from the most typical slow and progressive deterioration of symptoms to a rapid and abrupt decline of lung function. Rapid worsening of clinical course is due to superimposed complications and comorbidities that can develop in IPF patients, with a higher incidence rate compared to the general population. These conditions may require a different management of the patient and a therapy adjustment, and thus it is fundamental to recognize them. High Resolution Computed Tomography (HRCT) is sensitive, but not specific, in detecting these complications, and can evaluate the presence of radiological variations when previous examinations are available; it recognizes ground glass opacities or consolidation that can be related to a large spectrum of comorbidities, such as infection, lung cancer, or acute exacerbation. To reach the final diagnosis, a multidisciplinary discussion is required, particularly when the clinical context is related to imaging findings.
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spelling doaj.art-245c0146ef524d9f8f8d0f9979ece3712023-09-03T00:36:08ZengMDPI AGMedicina1010-660X2019-09-01551061310.3390/medicina55100613medicina55100613Imaging Review of the Lung Parenchymal Complications in Patients with IPFElisa Baratella0Ilaria Fiorese1Cristina Marrocchio2Francesco Salton3Maria Assunta Cova4Department of Radiology, Azienda Sanitaria Universitaria Integrata di Trieste (ASUITS), 34100 Trieste, ItalyDepartment of Radiology, Azienda Sanitaria Universitaria Integrata di Trieste (ASUITS), 34100 Trieste, ItalyDepartment of Radiology, Azienda Sanitaria Universitaria Integrata di Trieste (ASUITS), 34100 Trieste, ItalyDepartment of Pneumology, Azienda Sanitaria Universitaria Integrata di Trieste (ASUITS), 34100 Trieste, ItalyDepartment of Radiology, Azienda Sanitaria Universitaria Integrata di Trieste (ASUITS), 34100 Trieste, ItalyIdiopathic pulmonary fibrosis (IPF) is a chronic, pulmonary-limited, interstitial lung disease with a poor prognosis. This condition is characterized by different clinical scenarios, ranging from the most typical slow and progressive deterioration of symptoms to a rapid and abrupt decline of lung function. Rapid worsening of clinical course is due to superimposed complications and comorbidities that can develop in IPF patients, with a higher incidence rate compared to the general population. These conditions may require a different management of the patient and a therapy adjustment, and thus it is fundamental to recognize them. High Resolution Computed Tomography (HRCT) is sensitive, but not specific, in detecting these complications, and can evaluate the presence of radiological variations when previous examinations are available; it recognizes ground glass opacities or consolidation that can be related to a large spectrum of comorbidities, such as infection, lung cancer, or acute exacerbation. To reach the final diagnosis, a multidisciplinary discussion is required, particularly when the clinical context is related to imaging findings.https://www.mdpi.com/1010-660X/55/10/613IPFconsolidationground glassinfectionlung canceracute exacerbationHRCT
spellingShingle Elisa Baratella
Ilaria Fiorese
Cristina Marrocchio
Francesco Salton
Maria Assunta Cova
Imaging Review of the Lung Parenchymal Complications in Patients with IPF
Medicina
IPF
consolidation
ground glass
infection
lung cancer
acute exacerbation
HRCT
title Imaging Review of the Lung Parenchymal Complications in Patients with IPF
title_full Imaging Review of the Lung Parenchymal Complications in Patients with IPF
title_fullStr Imaging Review of the Lung Parenchymal Complications in Patients with IPF
title_full_unstemmed Imaging Review of the Lung Parenchymal Complications in Patients with IPF
title_short Imaging Review of the Lung Parenchymal Complications in Patients with IPF
title_sort imaging review of the lung parenchymal complications in patients with ipf
topic IPF
consolidation
ground glass
infection
lung cancer
acute exacerbation
HRCT
url https://www.mdpi.com/1010-660X/55/10/613
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AT cristinamarrocchio imagingreviewofthelungparenchymalcomplicationsinpatientswithipf
AT francescosalton imagingreviewofthelungparenchymalcomplicationsinpatientswithipf
AT mariaassuntacova imagingreviewofthelungparenchymalcomplicationsinpatientswithipf