Patchouli Alcohol Improves the Integrity of the Blood-Spinal Cord Barrier by Inhibiting Endoplasmic Reticulum Stress Through the Akt/CHOP/Caspase-3 Pathway Following Spinal Cord Injury

Patchouli Alcohol Improves the Integrity of the Blood-Spinal Cord Barrier by Inhibiting Endoplasmic Reticulum Stress Through the Akt/CHOP/Caspase-3 Pathway Following Spinal Cord Injury

Spinal cord injury (SCI) is a destructive and complex disorder of the central nervous system (CNS) for which there is no clinical treatment. Blood-spinal cord barrier (BSCB) rupture is a critical event in SCI that aggravates nerve injury. Therefore, maintaining the integrity of the BSCB may be a pot...

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Bibliographic Details
Main Authors: Chongan Huang, Weiqi Zhang, FeiFan Chu, Hao Qian, Yining Wang, Fangzhou Qi, Mengke Ye, Jiaying Zhou, Zhi Lin, ChenLin Dong, Xiangyang Wang, Qingqing Wang, Haiming Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
central nervous system
spinal cord injury
blood-spinal cord barrier
patchouli alcohol
endoplasmic reticulum stress
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.693533/full

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