Label-free adaptive optics single-molecule localization microscopy for whole zebrafish

Label-free adaptive optics single-molecule localization microscopy for whole zebrafish

Abstract Specimen-induced aberration has been a major factor limiting the imaging depth of single-molecule localization microscopy (SMLM). Here, we report the application of label-free wavefront sensing adaptive optics to SMLM for deep-tissue super-resolution imaging. The proposed system measures co...

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Bibliographic Details
Main Authors: Sanghyeon Park, Yonghyeon Jo, Minsu Kang, Jin Hee Hong, Sangyoon Ko, Suhyun Kim, Sangjun Park, Hae Chul Park, Sang-Hee Shim, Wonshik Choi
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39896-2

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