Percutaneous Mitral Valve Repair in Mitral Regurgitation Reduces Cell-Free Hemoglobin and Improves Endothelial Function.

Percutaneous Mitral Valve Repair in Mitral Regurgitation Reduces Cell-Free Hemoglobin and Improves Endothelial Function.

BACKGROUND AND OBJECTIVE:Endothelial dysfunction is predictive for cardiovascular events and may be caused by decreased bioavailability of nitric oxide (NO). NO is scavenged by cell-free hemoglobin with reduction of bioavailable NO up to 70% subsequently deteriorating vascular function. While patien...

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Bibliographic Details
Main Authors: Christos Rammos, Tobias Zeus, Jan Balzer, Laura Kubatz, Ulrike B Hendgen-Cotta, Verena Veulemans, Katharina Hellhammer, Matthias Totzeck, Peter Luedike, Malte Kelm, Tienush Rassaf
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4795750?pdf=render

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