Lsb1 is a negative regulator of las17 dependent actin polymerization involved in endocytosis.

The spatial and temporal regulation of actin polymerization is crucial for various cellular processes. Members of the Wiskott-Aldrich syndrome protein (WASP) family activate the Arp2/3-complex leading to actin polymerization. The yeast Saccharomyces cerevisiae contains only one WASP homolog, Las17,...

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Bibliographic Details
Main Authors: Matthias Spiess, Johan-Owen de Craene, Alphée Michelot, Bruno Rinaldi, Aline Huber, David G Drubin, Barbara Winsor, Sylvie Friant
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3620054?pdf=render