Study of the Role of the Tyrosine Kinase Receptor MerTK in the Development of Kidney Ischemia-Reperfusion Injury in RCS Rats

Study of the Role of the Tyrosine Kinase Receptor MerTK in the Development of Kidney Ischemia-Reperfusion Injury in RCS Rats

Renal ischaemia reperfusion (I/R) triggers a cascade of events including oxidative stress, apoptotic body and microparticle (MP) formation as well as an acute inflammatory process that may contribute to organ failure. Macrophages are recruited to phagocytose cell debris and MPs. The tyrosine kinase...

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Bibliographic Details
Main Authors: Thomas Pelé, Sebastien Giraud, Sandrine Joffrion, Virginie Ameteau, Adriana Delwail, Jean-Michel Goujon, Laurent Macchi, Thierry Hauet, Fatima Dkhissi, Omar Benzakour
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
ischemia-reperfusion
MerTK
microparticles
inflammation
phagocytosis
RCS rats
Online Access:https://www.mdpi.com/1422-0067/22/22/12103

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