Anaphylatoxin Receptors C3aR and C5aR1 Are Important Factors That Influence the Impact of Ethanol on the Adipose Secretome

Anaphylatoxin Receptors C3aR and C5aR1 Are Important Factors That Influence the Impact of Ethanol on the Adipose Secretome

Background and aims: Chronic ethanol exposure results in inflammation in adipose tissue; this response is associated with activation of complement as well as the development of alcohol-related liver disease (ALD). Adipose communicates with other organs, including liver, via the release of soluble me...

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Bibliographic Details
Main Authors: Rebecca L. McCullough, Megan R. McMullen, Kyle L. Poulsen, Adam Kim, M. Edward Medof, Laura E. Nagy
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Immunology
Subjects:
adipose
inflammation
secretome
complement
anaphylatoxin
alcoholic liver disease
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02133/full

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