Tissue Sodium Accumulation Induces Organ Inflammation and Injury in Chronic Kidney Disease

Tissue Sodium Accumulation Induces Organ Inflammation and Injury in Chronic Kidney Disease

High salt intake is a primary cause of over-hydration in chronic kidney disease (CKD) patients. Inflammatory markers are predictors of CKD mortality; however, the pathogenesis of inflammation remains unclear. Sodium storage in tissues has recently emerged as an issue of concern. The binding of sodiu...

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Bibliographic Details
Main Authors: Yasuhiko Ito, Ting Sun, Hiroya Tanaka, Makoto Yamaguchi, Hiroshi Kinashi, Fumiko Sakata, Shunnosuke Kunoki, Yukinao Sakai, Takuji Ishimoto
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
sodium storage
TonEBP
inflammation
organ dysfunction
IL-6
Online Access:https://www.mdpi.com/1422-0067/24/9/8329

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