Multilayer networks: aspects, implementations, and application in biomedicine
Abstract Modeling and analyses of complex systems using network theory have been an object of study for a long time. They have caught attention in many disciplines such as sociology, epidemiology, ecology, psychology, biology, biomedicine, and other fields. Network theory is especially an efficient...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2020-07-01
|
| Series: | Big Data Analytics |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s41044-020-00046-0 |
| _version_ | 1818844467250069504 |
|---|---|
| author | Zaynab Hammoud Frank Kramer |
| author_facet | Zaynab Hammoud Frank Kramer |
| author_sort | Zaynab Hammoud |
| collection | DOAJ |
| description | Abstract Modeling and analyses of complex systems using network theory have been an object of study for a long time. They have caught attention in many disciplines such as sociology, epidemiology, ecology, psychology, biology, biomedicine, and other fields. Network theory is especially an efficient tool to model biological networks such as gene co-expression networks, protein-protein interaction networks, or pathways. Considering the enhanced resolutions of complex real-world systems, the interest has been directed to multilayered networks. However, despite this surge of recent attention, the use of the multilayer framework in the biological field is still in its youth. In this paper, we review the different aspects and terminologies of multilayered networks. We also briefly discuss the variant applications of the multilayer framework, and finally, we give an overview of various existing applications of the multilayer model in network biology. |
| first_indexed | 2024-12-19T05:14:13Z |
| format | Article |
| id | doaj.art-2472bd617aa2495085688e8c5e73d542 |
| institution | Directory Open Access Journal |
| issn | 2058-6345 |
| language | English |
| last_indexed | 2024-12-19T05:14:13Z |
| publishDate | 2020-07-01 |
| publisher | BMC |
| record_format | Article |
| series | Big Data Analytics |
| spelling | doaj.art-2472bd617aa2495085688e8c5e73d5422022-12-21T20:34:44ZengBMCBig Data Analytics2058-63452020-07-015111810.1186/s41044-020-00046-0Multilayer networks: aspects, implementations, and application in biomedicineZaynab Hammoud0Frank Kramer1IT-Infrastructure for Translational Medical Research, University of AugsburgIT-Infrastructure for Translational Medical Research, University of AugsburgAbstract Modeling and analyses of complex systems using network theory have been an object of study for a long time. They have caught attention in many disciplines such as sociology, epidemiology, ecology, psychology, biology, biomedicine, and other fields. Network theory is especially an efficient tool to model biological networks such as gene co-expression networks, protein-protein interaction networks, or pathways. Considering the enhanced resolutions of complex real-world systems, the interest has been directed to multilayered networks. However, despite this surge of recent attention, the use of the multilayer framework in the biological field is still in its youth. In this paper, we review the different aspects and terminologies of multilayered networks. We also briefly discuss the variant applications of the multilayer framework, and finally, we give an overview of various existing applications of the multilayer model in network biology.http://link.springer.com/article/10.1186/s41044-020-00046-0Multilayered graphsGraph theoryNetwork biology |
| spellingShingle | Zaynab Hammoud Frank Kramer Multilayer networks: aspects, implementations, and application in biomedicine Big Data Analytics Multilayered graphs Graph theory Network biology |
| title | Multilayer networks: aspects, implementations, and application in biomedicine |
| title_full | Multilayer networks: aspects, implementations, and application in biomedicine |
| title_fullStr | Multilayer networks: aspects, implementations, and application in biomedicine |
| title_full_unstemmed | Multilayer networks: aspects, implementations, and application in biomedicine |
| title_short | Multilayer networks: aspects, implementations, and application in biomedicine |
| title_sort | multilayer networks aspects implementations and application in biomedicine |
| topic | Multilayered graphs Graph theory Network biology |
| url | http://link.springer.com/article/10.1186/s41044-020-00046-0 |
| work_keys_str_mv | AT zaynabhammoud multilayernetworksaspectsimplementationsandapplicationinbiomedicine AT frankkramer multilayernetworksaspectsimplementationsandapplicationinbiomedicine |