Effect of acetaminophen on relieving orthodontic pain with clear aligner based on GAD-7: A retrospective research
Objectives: Patients may have uncomfortable feelings during orthodontic treatment, which can directly lead to dissatisfaction. So in order to improve the patient's sense of pleasure during the treatment, it would be of great benefit if orthodontic pain can be relieved. Materials and methods: We...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-01-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844023105007 |
| _version_ | 1797337009810833408 |
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| author | Yunan Gao Rui Wang Qiong Liu Bo Zhou Hu Qiao |
| author_facet | Yunan Gao Rui Wang Qiong Liu Bo Zhou Hu Qiao |
| author_sort | Yunan Gao |
| collection | DOAJ |
| description | Objectives: Patients may have uncomfortable feelings during orthodontic treatment, which can directly lead to dissatisfaction. So in order to improve the patient's sense of pleasure during the treatment, it would be of great benefit if orthodontic pain can be relieved. Materials and methods: We included 150 patients wearing clear aligners from 18 to 30 years old during 2018–2020. Then designed following groups to determine the effectiveness of both verbal behavior modification and combination therapy with acetaminophen in reducing treatment pain: Group A, generalized anxiety disorder 7 (GAD-7) scored 0–4; Group B, GAD-7 scored 5–9; Group C, GAD-7 scored 10–14; and Group D, GAD-7 scored 15–21. Results: There was a difference in the visual analog scale (VAS) between verbal behavior modification with and without a 300-mg acetaminophen tablet oral QD in Group A (received the intervention at 8 h and 1 d), Group B at 8 h and 1 d, Group C at 8 h, 1 d, 2 d, and 3 d, and Group D at 8 h, 1 d, 2 d, 3 d, and 4 d. After 8 h, 1 d, 2 d, 3 d, and 4 d in patients with verbal behavior modification, VAS was markedly increased in Group D compared with Group A, B and C. Furthermore, after 8 h and 1 d in patients with verbal behavior modification and 300-mg acetaminophen tablet oral QD, VAS was strongly enhanced in Group D. Conclusions: Dental anxiety is strongly associated with pain in orthodontic patients receiving clear aligners. Acetaminophen administration may be a benefit in orthodontic pain that results from clear aligners, especially in the group with more GAD-7. |
| first_indexed | 2024-03-08T09:03:11Z |
| format | Article |
| id | doaj.art-2473d30e20c64889ae6f211fb12b229e |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-03-08T09:03:11Z |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-2473d30e20c64889ae6f211fb12b229e2024-02-01T06:31:21ZengElsevierHeliyon2405-84402024-01-01101e23292Effect of acetaminophen on relieving orthodontic pain with clear aligner based on GAD-7: A retrospective researchYunan Gao0Rui Wang1Qiong Liu2Bo Zhou3Hu Qiao4Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, Shaanxi, ChinaKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, Shaanxi, ChinaKey Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, Shaanxi, ChinaRespiratory and Critical Care Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China; Corresponding author. Respiratory and critical care medicine, the First Affiliated Hospital of Xi'an Jiaotong University, Yanta West Road, Xi'an, Shaanxi 710000, China.Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, Shaanxi, China; Corresponding author. College of Stomatology, Xi'an Jiaotong University, Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, 98# Xiwu Road, Xi'an, Shaanxi 710004, China.Objectives: Patients may have uncomfortable feelings during orthodontic treatment, which can directly lead to dissatisfaction. So in order to improve the patient's sense of pleasure during the treatment, it would be of great benefit if orthodontic pain can be relieved. Materials and methods: We included 150 patients wearing clear aligners from 18 to 30 years old during 2018–2020. Then designed following groups to determine the effectiveness of both verbal behavior modification and combination therapy with acetaminophen in reducing treatment pain: Group A, generalized anxiety disorder 7 (GAD-7) scored 0–4; Group B, GAD-7 scored 5–9; Group C, GAD-7 scored 10–14; and Group D, GAD-7 scored 15–21. Results: There was a difference in the visual analog scale (VAS) between verbal behavior modification with and without a 300-mg acetaminophen tablet oral QD in Group A (received the intervention at 8 h and 1 d), Group B at 8 h and 1 d, Group C at 8 h, 1 d, 2 d, and 3 d, and Group D at 8 h, 1 d, 2 d, 3 d, and 4 d. After 8 h, 1 d, 2 d, 3 d, and 4 d in patients with verbal behavior modification, VAS was markedly increased in Group D compared with Group A, B and C. Furthermore, after 8 h and 1 d in patients with verbal behavior modification and 300-mg acetaminophen tablet oral QD, VAS was strongly enhanced in Group D. Conclusions: Dental anxiety is strongly associated with pain in orthodontic patients receiving clear aligners. Acetaminophen administration may be a benefit in orthodontic pain that results from clear aligners, especially in the group with more GAD-7.http://www.sciencedirect.com/science/article/pii/S2405844023105007Clear alignersGAD-7AcetaminophenOrthodontic painVerbal behavior modification |
| spellingShingle | Yunan Gao Rui Wang Qiong Liu Bo Zhou Hu Qiao Effect of acetaminophen on relieving orthodontic pain with clear aligner based on GAD-7: A retrospective research Heliyon Clear aligners GAD-7 Acetaminophen Orthodontic pain Verbal behavior modification |
| title | Effect of acetaminophen on relieving orthodontic pain with clear aligner based on GAD-7: A retrospective research |
| title_full | Effect of acetaminophen on relieving orthodontic pain with clear aligner based on GAD-7: A retrospective research |
| title_fullStr | Effect of acetaminophen on relieving orthodontic pain with clear aligner based on GAD-7: A retrospective research |
| title_full_unstemmed | Effect of acetaminophen on relieving orthodontic pain with clear aligner based on GAD-7: A retrospective research |
| title_short | Effect of acetaminophen on relieving orthodontic pain with clear aligner based on GAD-7: A retrospective research |
| title_sort | effect of acetaminophen on relieving orthodontic pain with clear aligner based on gad 7 a retrospective research |
| topic | Clear aligners GAD-7 Acetaminophen Orthodontic pain Verbal behavior modification |
| url | http://www.sciencedirect.com/science/article/pii/S2405844023105007 |
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