A review of combined neuromodulation and physical therapy interventions for enhanced neurorehabilitation
Rehabilitation approaches for individuals with neurologic conditions have increasingly shifted toward promoting neuroplasticity for enhanced recovery and restoration of function. This review focuses on exercise strategies and non-invasive neuromodulation techniques that target neuroplasticity, inclu...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-07-01
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| Series: | Frontiers in Human Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnhum.2023.1151218/full |
| _version_ | 1797775605422358528 |
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| author | Alexandra Evancho William J. Tyler William J. Tyler Keith McGregor |
| author_facet | Alexandra Evancho William J. Tyler William J. Tyler Keith McGregor |
| author_sort | Alexandra Evancho |
| collection | DOAJ |
| description | Rehabilitation approaches for individuals with neurologic conditions have increasingly shifted toward promoting neuroplasticity for enhanced recovery and restoration of function. This review focuses on exercise strategies and non-invasive neuromodulation techniques that target neuroplasticity, including transcranial magnetic stimulation (TMS), vagus nerve stimulation (VNS), and peripheral nerve stimulation (PNS). We have chosen to focus on non-invasive neuromodulation techniques due to their greater potential for integration into routine clinical practice. We explore and discuss the application of these interventional strategies in four neurological conditions that are frequently encountered in rehabilitation settings: Parkinson’s Disease (PD), Traumatic Brain Injury (TBI), stroke, and Spinal Cord Injury (SCI). Additionally, we discuss the potential benefits of combining non-invasive neuromodulation with rehabilitation, which has shown promise in accelerating recovery. Our review identifies studies that demonstrate enhanced recovery through combined exercise and non-invasive neuromodulation in the selected patient populations. We primarily focus on the motor aspects of rehabilitation, but also briefly address non-motor impacts of these conditions. Additionally, we identify the gaps in current literature and barriers to implementation of combined approaches into clinical practice. We highlight areas needing further research and suggest avenues for future investigation, aiming to enhance the personalization of the unique neuroplastic responses associated with each condition. This review serves as a resource for rehabilitation professionals and researchers seeking a comprehensive understanding of neuroplastic exercise interventions and non-invasive neuromodulation techniques tailored for specific diseases and diagnoses. |
| first_indexed | 2024-03-12T22:38:08Z |
| format | Article |
| id | doaj.art-24760cc4dd94460a90902d46f90f2518 |
| institution | Directory Open Access Journal |
| issn | 1662-5161 |
| language | English |
| last_indexed | 2024-03-12T22:38:08Z |
| publishDate | 2023-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Human Neuroscience |
| spelling | doaj.art-24760cc4dd94460a90902d46f90f25182023-07-21T11:19:57ZengFrontiers Media S.A.Frontiers in Human Neuroscience1662-51612023-07-011710.3389/fnhum.2023.11512181151218A review of combined neuromodulation and physical therapy interventions for enhanced neurorehabilitationAlexandra Evancho0William J. Tyler1William J. Tyler2Keith McGregor3Department of Physical Therapy, School of Health Professions, University of Alabama at Birmingham, Birmingham, AL, United StatesDepartment of Biomedical Engineering, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United StatesDepartment of Physical Medicine and Rehabilitation, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United StatesDepartment of Clinical and Diagnostic Studies, School of Health Professions, University of Alabama at Birmingham, Birmingham, AL, United StatesRehabilitation approaches for individuals with neurologic conditions have increasingly shifted toward promoting neuroplasticity for enhanced recovery and restoration of function. This review focuses on exercise strategies and non-invasive neuromodulation techniques that target neuroplasticity, including transcranial magnetic stimulation (TMS), vagus nerve stimulation (VNS), and peripheral nerve stimulation (PNS). We have chosen to focus on non-invasive neuromodulation techniques due to their greater potential for integration into routine clinical practice. We explore and discuss the application of these interventional strategies in four neurological conditions that are frequently encountered in rehabilitation settings: Parkinson’s Disease (PD), Traumatic Brain Injury (TBI), stroke, and Spinal Cord Injury (SCI). Additionally, we discuss the potential benefits of combining non-invasive neuromodulation with rehabilitation, which has shown promise in accelerating recovery. Our review identifies studies that demonstrate enhanced recovery through combined exercise and non-invasive neuromodulation in the selected patient populations. We primarily focus on the motor aspects of rehabilitation, but also briefly address non-motor impacts of these conditions. Additionally, we identify the gaps in current literature and barriers to implementation of combined approaches into clinical practice. We highlight areas needing further research and suggest avenues for future investigation, aiming to enhance the personalization of the unique neuroplastic responses associated with each condition. This review serves as a resource for rehabilitation professionals and researchers seeking a comprehensive understanding of neuroplastic exercise interventions and non-invasive neuromodulation techniques tailored for specific diseases and diagnoses.https://www.frontiersin.org/articles/10.3389/fnhum.2023.1151218/fullneuromodulationneuroplasticityrehabilitationvagus nerve stimulationtranscranial magnetic stimulationperipheral nerve stimulation |
| spellingShingle | Alexandra Evancho William J. Tyler William J. Tyler Keith McGregor A review of combined neuromodulation and physical therapy interventions for enhanced neurorehabilitation Frontiers in Human Neuroscience neuromodulation neuroplasticity rehabilitation vagus nerve stimulation transcranial magnetic stimulation peripheral nerve stimulation |
| title | A review of combined neuromodulation and physical therapy interventions for enhanced neurorehabilitation |
| title_full | A review of combined neuromodulation and physical therapy interventions for enhanced neurorehabilitation |
| title_fullStr | A review of combined neuromodulation and physical therapy interventions for enhanced neurorehabilitation |
| title_full_unstemmed | A review of combined neuromodulation and physical therapy interventions for enhanced neurorehabilitation |
| title_short | A review of combined neuromodulation and physical therapy interventions for enhanced neurorehabilitation |
| title_sort | review of combined neuromodulation and physical therapy interventions for enhanced neurorehabilitation |
| topic | neuromodulation neuroplasticity rehabilitation vagus nerve stimulation transcranial magnetic stimulation peripheral nerve stimulation |
| url | https://www.frontiersin.org/articles/10.3389/fnhum.2023.1151218/full |
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