Assessment of Relationship between Spontaneous Abortion and Occupational Exposure to Organic Solvents
Introduction & Objective: Nowadays, some studies indicate the adverse effects of exposure to chemicals, especially organic solvents on the reproductive system of females. This study aimed to assess the relationship between spontaneous abortion with occupational exposure to organic solvents in p...
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Format: | Article |
Language: | fas |
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Yasuj University Of Medical Sciences
2011-04-01
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Series: | Armaghane Danesh Bimonthly Journal |
Subjects: | |
Online Access: | http://armaghanj.yums.ac.ir/browse.php?a_code=A-10-1-287&slc_lang=en&sid=1 |
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author | S Mohammadi Y Labbafinejad E Mirzamohammadi F Rahimpour M Malek MS Attarchi |
author_facet | S Mohammadi Y Labbafinejad E Mirzamohammadi F Rahimpour M Malek MS Attarchi |
author_sort | S Mohammadi |
collection | DOAJ |
description | Introduction & Objective: Nowadays, some studies indicate the adverse effects of exposure to chemicals, especially organic solvents on the reproductive system of females. This study aimed to assess the relationship between spontaneous abortion with occupational exposure to organic solvents in pharmaceutical industry.
Materials & Methods: This is a cross-sectional and descriptive-analytical study which was carried out in 2010 in one of the pharmaceutical factories located in the suburbs of Tehran. During the study, married women who were working in the factory laboratory units and were exposed to mixed organic solvents were compared with married women who were working in the packing units of the factory without occupational exposure to organic solvents. Frequency of spontaneous abortion and duration of pregnancy were assessed in both two groups. Collected data were analyzed with the SPSS software using t-test, logistic regression, and chi-square test.
Results: In the present study, the frequency of spontaneous abortion in employees with exposure to organic solvents mixture was 10.7%. This study showed that even after adjustment for confounding factors, there was a significant correlation between spontaneous abortion and occupational exposure to organic solvents mixture and this correlation increased with increasing levels of exposure to organic solvents. Moreover, a significant correlation was observed between occupational exposure to mixed organic solvents and waiting time to become pregnant (TTP). Furthermore, this study showed that even after adjustment for confounding variables, shift workers were significantly more affected by spontaneous abortion compared to daytime workers (P < 0.001).
Conclusion: According to the results of this study, since there is probability of spontaneous abortion resulting from occupational exposure to various chemicals including organic solvents, review of the status of occupational exposure of workers can be helpful in improving the reproductive health of female workers. |
first_indexed | 2024-04-11T09:01:25Z |
format | Article |
id | doaj.art-247c97ef4f7742ea8a110bf8732278d3 |
institution | Directory Open Access Journal |
issn | 1728-6506 1728-6514 |
language | fas |
last_indexed | 2024-04-11T09:01:25Z |
publishDate | 2011-04-01 |
publisher | Yasuj University Of Medical Sciences |
record_format | Article |
series | Armaghane Danesh Bimonthly Journal |
spelling | doaj.art-247c97ef4f7742ea8a110bf8732278d32022-12-22T04:32:46ZfasYasuj University Of Medical SciencesArmaghane Danesh Bimonthly Journal1728-65061728-65142011-04-011616979Assessment of Relationship between Spontaneous Abortion and Occupational Exposure to Organic SolventsS Mohammadi0Y Labbafinejad1E Mirzamohammadi2F Rahimpour3M Malek4MS Attarchi5 Introduction & Objective: Nowadays, some studies indicate the adverse effects of exposure to chemicals, especially organic solvents on the reproductive system of females. This study aimed to assess the relationship between spontaneous abortion with occupational exposure to organic solvents in pharmaceutical industry. Materials & Methods: This is a cross-sectional and descriptive-analytical study which was carried out in 2010 in one of the pharmaceutical factories located in the suburbs of Tehran. During the study, married women who were working in the factory laboratory units and were exposed to mixed organic solvents were compared with married women who were working in the packing units of the factory without occupational exposure to organic solvents. Frequency of spontaneous abortion and duration of pregnancy were assessed in both two groups. Collected data were analyzed with the SPSS software using t-test, logistic regression, and chi-square test. Results: In the present study, the frequency of spontaneous abortion in employees with exposure to organic solvents mixture was 10.7%. This study showed that even after adjustment for confounding factors, there was a significant correlation between spontaneous abortion and occupational exposure to organic solvents mixture and this correlation increased with increasing levels of exposure to organic solvents. Moreover, a significant correlation was observed between occupational exposure to mixed organic solvents and waiting time to become pregnant (TTP). Furthermore, this study showed that even after adjustment for confounding variables, shift workers were significantly more affected by spontaneous abortion compared to daytime workers (P < 0.001). Conclusion: According to the results of this study, since there is probability of spontaneous abortion resulting from occupational exposure to various chemicals including organic solvents, review of the status of occupational exposure of workers can be helpful in improving the reproductive health of female workers.http://armaghanj.yums.ac.ir/browse.php?a_code=A-10-1-287&slc_lang=en&sid=1Organic solvent Occupational exposure Abortion |
spellingShingle | S Mohammadi Y Labbafinejad E Mirzamohammadi F Rahimpour M Malek MS Attarchi Assessment of Relationship between Spontaneous Abortion and Occupational Exposure to Organic Solvents Armaghane Danesh Bimonthly Journal Organic solvent Occupational exposure Abortion |
title | Assessment of Relationship between Spontaneous Abortion and Occupational Exposure to Organic Solvents |
title_full | Assessment of Relationship between Spontaneous Abortion and Occupational Exposure to Organic Solvents |
title_fullStr | Assessment of Relationship between Spontaneous Abortion and Occupational Exposure to Organic Solvents |
title_full_unstemmed | Assessment of Relationship between Spontaneous Abortion and Occupational Exposure to Organic Solvents |
title_short | Assessment of Relationship between Spontaneous Abortion and Occupational Exposure to Organic Solvents |
title_sort | assessment of relationship between spontaneous abortion and occupational exposure to organic solvents |
topic | Organic solvent Occupational exposure Abortion |
url | http://armaghanj.yums.ac.ir/browse.php?a_code=A-10-1-287&slc_lang=en&sid=1 |
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