Identification of Immunoglobulin Gene Rearrangement Biomarkers in Multiple Myeloma through cfDNA-Based Liquid Biopsy Using tchDNA-Seq

Identification of Immunoglobulin Gene Rearrangement Biomarkers in Multiple Myeloma through cfDNA-Based Liquid Biopsy Using tchDNA-Seq

Multiple myeloma (MM) is a hematological malignancy characterized by the clonal proliferation of pathogenic CD138+ plasma cells (PPCs) in bone marrow (BM). Recent years have seen a significant increase in the treatment options for MM; however, most patients who achieve complete the response ultimate...

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Bibliographic Details
Main Authors: Natalia Buenache, Andrea Sánchez-delaCruz, Isabel Cuenca, Alicia Giménez, Laura Moreno, Joaquín Martínez-López, Juan Manuel Rosa-Rosa
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Cancers
Subjects:
liquid biopsy
IG rearrangements
tchDNAseq
Online Access:https://www.mdpi.com/2072-6694/15/11/2911

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