ANALYSIS OF THE BASELINE DRIFT ARTIFACT IN HADAMARD TRANSFORM SEPARATION TECHNIQUES

The baseline drift artifact (BDA), namely, the baseline bias between the Hadamard transform (HT) spectrum and the signal averaging (SA) spectrum was unfortunately found in the HT pulsed separation techniques, which makes the HT analytical chemistry face the challenge of non-stability and unreliabili...

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Main Authors: Yan Hong, Jingming Su, Chaoli Tang, Chaoqun Huang, Sheng Liu, Yannan Chu
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2020-03-01
Series:Química Nova
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422020000100066&tlng=en
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author Yan Hong
Jingming Su
Chaoli Tang
Chaoqun Huang
Sheng Liu
Yannan Chu
author_facet Yan Hong
Jingming Su
Chaoli Tang
Chaoqun Huang
Sheng Liu
Yannan Chu
author_sort Yan Hong
collection DOAJ
description The baseline drift artifact (BDA), namely, the baseline bias between the Hadamard transform (HT) spectrum and the signal averaging (SA) spectrum was unfortunately found in the HT pulsed separation techniques, which makes the HT analytical chemistry face the challenge of non-stability and unreliability. In order to find out the origin and eliminate the BDA phenomenon, the multiplexing mechanism of Hadamard transform ion mobility spectrometry (HT-IMS) has been analyzed in this research. Through simulation and experimental comparisons, the non-ideal overlap defect in Hadamard multiplexing process was suggested as the cause for the BDA phenomenon. Eventually, with a correction method, the BDA phenomenon could be well addressed, which guarantees the reliability and stability of HT techniques without increasing the hardware complexity.
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spelling doaj.art-247e538c911c4272bd4523404aa20afc2022-12-22T04:16:15ZengSociedade Brasileira de QuímicaQuímica Nova1678-70642020-03-01431667110.21577/0100-4042.20170434ANALYSIS OF THE BASELINE DRIFT ARTIFACT IN HADAMARD TRANSFORM SEPARATION TECHNIQUESYan HongJingming SuChaoli TangChaoqun Huanghttps://orcid.org/0000-0003-2862-6024Sheng LiuYannan ChuThe baseline drift artifact (BDA), namely, the baseline bias between the Hadamard transform (HT) spectrum and the signal averaging (SA) spectrum was unfortunately found in the HT pulsed separation techniques, which makes the HT analytical chemistry face the challenge of non-stability and unreliability. In order to find out the origin and eliminate the BDA phenomenon, the multiplexing mechanism of Hadamard transform ion mobility spectrometry (HT-IMS) has been analyzed in this research. Through simulation and experimental comparisons, the non-ideal overlap defect in Hadamard multiplexing process was suggested as the cause for the BDA phenomenon. Eventually, with a correction method, the BDA phenomenon could be well addressed, which guarantees the reliability and stability of HT techniques without increasing the hardware complexity.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422020000100066&tlng=enbaseline drift artifactHadamard transformmultiplexing mechanismcorrection
spellingShingle Yan Hong
Jingming Su
Chaoli Tang
Chaoqun Huang
Sheng Liu
Yannan Chu
ANALYSIS OF THE BASELINE DRIFT ARTIFACT IN HADAMARD TRANSFORM SEPARATION TECHNIQUES
Química Nova
baseline drift artifact
Hadamard transform
multiplexing mechanism
correction
title ANALYSIS OF THE BASELINE DRIFT ARTIFACT IN HADAMARD TRANSFORM SEPARATION TECHNIQUES
title_full ANALYSIS OF THE BASELINE DRIFT ARTIFACT IN HADAMARD TRANSFORM SEPARATION TECHNIQUES
title_fullStr ANALYSIS OF THE BASELINE DRIFT ARTIFACT IN HADAMARD TRANSFORM SEPARATION TECHNIQUES
title_full_unstemmed ANALYSIS OF THE BASELINE DRIFT ARTIFACT IN HADAMARD TRANSFORM SEPARATION TECHNIQUES
title_short ANALYSIS OF THE BASELINE DRIFT ARTIFACT IN HADAMARD TRANSFORM SEPARATION TECHNIQUES
title_sort analysis of the baseline drift artifact in hadamard transform separation techniques
topic baseline drift artifact
Hadamard transform
multiplexing mechanism
correction
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422020000100066&tlng=en
work_keys_str_mv AT yanhong analysisofthebaselinedriftartifactinhadamardtransformseparationtechniques
AT jingmingsu analysisofthebaselinedriftartifactinhadamardtransformseparationtechniques
AT chaolitang analysisofthebaselinedriftartifactinhadamardtransformseparationtechniques
AT chaoqunhuang analysisofthebaselinedriftartifactinhadamardtransformseparationtechniques
AT shengliu analysisofthebaselinedriftartifactinhadamardtransformseparationtechniques
AT yannanchu analysisofthebaselinedriftartifactinhadamardtransformseparationtechniques