The mechanism of TiaoGanYiPi formula for treating chronic hepatitis B by network pharmacology and molecular docking verification

The mechanism of TiaoGanYiPi formula for treating chronic hepatitis B by network pharmacology and molecular docking verification

Abstract The Chinese herbal formula TiaoGanYiPi (TGYP) showed effective against chronic hepatitis B (CHB) caused by hepatitis B virus (HBV) infection. Hence, we aimed to clarify the mechanisms and potential targets between TGYP and CHB. The active compounds and related putative targets of TGYP, and...

Full description

Bibliographic Details
Main Authors:	Xu Cao, Xiaobin Zao, Baiquan Xue, Hening Chen, Jiaxin Zhang, Shuo Li, Xiaobin Li, Shun Zhu, Rui Guo, Xiaoke Li, Yong’an Ye
Format:	Article
Language:	English
Published:	Nature Portfolio 2021-04-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-021-87812-9

Similar Items

Network pharmacology and in vitro experiments-based strategy to investigate the mechanisms of KangXianYiAi formula for hepatitis B virus-related hepatocellular carcinoma
by: Xu Cao, et al.
Published: (2022-09-01)

The Chinese herbal KangXianYiAi formula inhibits hepatocellular carcinoma by reducing glutathione and inducing ferroptosis
by: Xiaobin Zao, et al.
Published: (2023-09-01)

Exploring the mechanism of JiGuCao capsule formula on treating hepatitis B virus infection via network pharmacology analysis and in vivo/vitro experiment verification
by: Xu Cao, et al.
Published: (2023-06-01)

Systematic review: Clinical outcomes of discontinuation of oral antivirals in hepatitis B-related liver cirrhosis
by: Yuhao Yao, et al.
Published: (2022-11-01)

Xie Zhuo Tiao Zhi formula ameliorates chronic alcohol-induced liver injury in mice
by: Kaixin Chang, et al.
Published: (2024-04-01)

Integrated analysis of single-cell and bulk RNA-sequencing reveals tumor heterogeneity and a signature based on NK cell marker genes for predicting prognosis in hepatocellular carcinoma
by: Shuo Li, et al.
Published: (2023-06-01)

Inheritance and Protection of the Historical and Cultural Heritage of Yunnan Ethnic Minorities—Taking the Yi Ethnic Group's "Ah Xi Tiao Yue" as an Example
by: Wen Zhang, et al.
Published: (2024-02-01)

Network Pharmacology and Experimental Verification Strategies to Illustrate the Mechanism of Jian-Pi-Yi-Shen Formula in Suppressing Epithelial–Mesenchymal Transition
by: Yuan Zhao, et al.
Published: (2022-05-01)

Identification of pseudo-immune tolerance for chronic hepatitis B patients: Development and validation of a non-invasive prediction model
by: Shuo Li, et al.
Published: (2023-04-01)

Najib de hui ying : ke fu zuo ri de kun nan, je jue jin ri zhen yi, ying xiang ming ri de tiao zhan /
by: Khairil Annas Jusoh, et al.
Published: (2010)

Impact of Algorithm Selection on Modeling Ozone Pollution: A Perspective on Box and Tiao (1975)
by: Mihaela Paun, et al.
Published: (2020-12-01)

Three Qinghao formulae for treating epidemics (wen yi)
by: Weihau, P, et al.
Published: (2020)

A Non-invasive Model for Predicting Liver Inflammation in Chronic Hepatitis B Patients With Normal Serum Alanine Aminotransferase Levels
by: Xiaoke Li, et al.
Published: (2021-06-01)

Computational systems pharmacology analysis of Tong-Jing-Yi formula in the treatment of dysmenorrhea
by: Yueyan Li, et al.
Published: (2022-04-01)

On analyzing the effects of policy interventions : Box-Jenkins and Box-Tiao vs. structural equation models
by: Hibbs, Douglas A., 1944-
Published: (2013)

Chinese medicine in the treatment of non-alcoholic fatty liver disease based on network pharmacology: a review
by: Shihao Zheng, et al.
Published: (2024-04-01)

Application of Network Pharmacology to Explore the Mechanism of Yi Xin Tai Formula in Treating Heart Failure
by: Wei Jia-Ming, et al.
Published: (2019-12-01)

JianPiYiShen formula prevents cisplatin-induced acute kidney injury in mice by improving necroptosis through MAPK pathway
by: Zhongtang Li, et al.
Published: (2024-02-01)

Involvement of Circulating Exosomal MicroRNAs in Jian-Pi-Yi-Shen Formula Protection Against Adenine-Induced Chronic Kidney Disease
by: Xinhui Liu, et al.
Published: (2021-02-01)

Exploring the molecular mechanism of Gan Shuang granules for the treatment of non-alcoholic steatohepatitis using network pharmacology, molecular docking, and experimental verification
by: Guoguo Zhi, et al.
Published: (2023-01-01)

Chinese herb mix Tiáo-Gēng-Tāng possesses antiaging and antioxidative effects and upregulates expression of estrogen receptors alpha and beta in ovariectomized rats
by: Xu Lian-wei, et al.
Published: (2011-12-01)

Qian Yi, Super Pediatrician
by: Min Li, et al.
Published: (2016-07-01)

Study on the Flavor Compounds of Fo Tiao Qiang under Different Thawing Methods Based on GC–IMS and Electronic Tongue Technology
by: Ruirong Lin, et al.
Published: (2022-05-01)

ANALYSIS OF ANTHROPONYMS IN THE MANUSCRIPT «QISSA-YI DJENKNAME-YI RISALE-YI SHAH-I MERDAN»
by: N. Kairanbayeva, et al.
Published: (2022-07-01)

ANALYSIS OF ANTHROPONYMS IN THE MANUSCRIPT «QISSA-YI DJENKNAME-YI RISALE-YI SHAH-I MERDAN»
by: N. Kairanbayeva, et al.
Published: (2022-06-01)

Identification of Active Compounds From Yi Nationality Herbal Formula Wosi Influencing COX-2 and VCAM-1 Signaling
by: Ji-Zhong Zhang, et al.
Published: (2020-11-01)

Ethnic flows in the Tibetan-Yi corridor throughout history
by: Shuo Shi
Published: (2018-06-01)

Chinese herbal decoction, Yi-Qi-Jian-Pi formula exerts anti-hepatic fibrosis effects in mouse models of CCl4-induced liver fibrosis
by: Shiyan Yang, et al.
Published: (2024-03-01)

Jian-Pi-Yi-Shen Formula Improves Adenine-Induced Chronic Kidney Disease via Regulating Tryptophan Metabolism and Aryl Hydrocarbon Receptor Signaling
by: Xinhui Liu, et al.
Published: (2022-07-01)

Mechanism of action of Bu Zhong Yi Qi Decoction in the treatment of chronic fatigue syndrome based on network pharmacology and molecular docking
by: Jie Zhang, et al.
Published: (2022-09-01)

Correction of water-penetrating velocity attenuation formula for “Pie” fragment
by: Zhang Lei, et al.
Published: (2019-06-01)

Pharmacological effects and mechanisms of YiYiFuZi powder in chronic heart disease revealed by metabolomics and network pharmacology
by: Yuming Wang, et al.
Published: (2023-06-01)

Network Pharmacology, Molecular Docking, and Experimental Verification to Reveal the Mitophagy-Associated Mechanism of Tangshen Formula in the Treatment of Diabetic Nephropathy
by: Chen Y, et al.
Published: (2024-02-01)

Yi-Qi-Jian-Pi Formula Suppresses RIPK1/RIPK3-Complex-Dependent Necroptosis of Hepatocytes Through ROS Signaling and Attenuates Liver Injury in Vivo and in Vitro
by: Feixia Wang, et al.
Published: (2021-04-01)

Efficacy and indication optimization of Chinese medicine (Tiao-Chang Ke-Min granules) for diarrhea-predominant irritable bowel syndrome: study protocol for a randomized controlled trial
by: Qian Li, et al.
Published: (2018-07-01)

Increasing prevalence of overweight and obesity in Yi farmers and migrants from 2007 to 2015 in China: the Yi migrant study
by: Ye Wang, et al.
Published: (2018-05-01)

Yi-Gan San Restores Behavioral Alterations and a Decrease of Brain Glutathione Level in a Mouse Model of Schizophrenia
by: Manabu Makinodan M.D., et al.
Published: (2009-01-01)

Yi-Gan San Restores Behavioral Alterations and a Decrease of Brain Glutathione Level in a Mouse Model of Schizophrenia
by: Manabu Makinodan, et al.
Published: (2009-02-01)

Nominalization in Nuosu Yi
by: Liu, Hongyong, et al.
Published: (2015)

Profesor Yi Lijun
by: Zhao Gang
Published: (2020-12-01)