Five Methods Comparison of 10 Years Cardiovascular Disease Risk Estimation in the Community in Sleman-Yogyakarta
Cardiovascular disease is the highest cause of death with total of 17.5 million deaths in the world. Nowadays there have beenexists many methods to calculate the risk of cardiovascular disease within the next 10 years, 5 of them are Framingham Risk Score (FRS) BMI and Cholesterol, Pooled Cohort Equa...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Indonesian |
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Universitas Gadjah Mada
2018-07-01
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| Series: | Jurnal Manajemen dan Pelayanan Farmasi |
| Subjects: | |
| Online Access: | https://jurnal.ugm.ac.id/jmpf/article/view/34469 |
| _version_ | 1819067679069175808 |
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| author | Clarentia Dwivani Herlina Herlina Karina Harijadi Budianto Budianto Rita Suhadi |
| author_facet | Clarentia Dwivani Herlina Herlina Karina Harijadi Budianto Budianto Rita Suhadi |
| author_sort | Clarentia Dwivani |
| collection | DOAJ |
| description | Cardiovascular disease is the highest cause of death with total of 17.5 million deaths in the world. Nowadays there have beenexists many methods to calculate the risk of cardiovascular disease within the next 10 years, 5 of them are Framingham Risk Score (FRS) BMI and Cholesterol, Pooled Cohort Equations (PCE), CV Risk Calculator, and Systematic Coronary Risk Evaluation (SCORE). The aim of this study waiss to compare the 5 methods of 10-year risk of cardiovascular disease based on mean values, risk categories, and statin recommendation. This observational analytic study was done with cross-sectional design. There were 169 respondents in Sleman, Yogyakarta who participated to this study. Normality of risk measurement data was performed using Kolmogorov-Smirnov test and comparative test was performed using Repeated ANOVA. Both proportion of risk categorization and statin therapy was calculated using the Marginal Homogeneity test. The average risk of FRS (BMI and Cholesterol), PCE, CV Risk Calculator, and SCORE were 14,6±11,7% (medium risk), 13,3±11,3% (medium risk), 6,8±6,4% (medium risk), 6,8±6,4% (medium risk), and 2,6±3,5% (medium risk). There were significant differences from the comparison between among methods on mean values and risk categories (p <0.01), except on PCE with FRS BMI (p=0.11) and PCE with CVRiskcalculator (p = 1.00). Comparison of statin therapy recommendation among FRS Cholesterol with PCE, FRS Cholesterol with SCORE, and PCE with FRS BMI methods showed significant differences (p <0.01), whereas FRS Cholesterol with FRS BMI and PCE with SCORE were not significantly different (p = 0,06 and p = 0,05). |
| first_indexed | 2024-12-21T16:22:05Z |
| format | Article |
| id | doaj.art-2481ae84fa0d4ebfa1ab541add6c27ea |
| institution | Directory Open Access Journal |
| issn | 2088-8139 2443-2946 |
| language | Indonesian |
| last_indexed | 2024-12-21T16:22:05Z |
| publishDate | 2018-07-01 |
| publisher | Universitas Gadjah Mada |
| record_format | Article |
| series | Jurnal Manajemen dan Pelayanan Farmasi |
| spelling | doaj.art-2481ae84fa0d4ebfa1ab541add6c27ea2022-12-21T18:57:33ZindUniversitas Gadjah MadaJurnal Manajemen dan Pelayanan Farmasi2088-81392443-29462018-07-0182596910.22146/jmpf.3446921669Five Methods Comparison of 10 Years Cardiovascular Disease Risk Estimation in the Community in Sleman-YogyakartaClarentia Dwivani0Herlina Herlina1Karina Harijadi2Budianto Budianto3Rita Suhadi4Faculty of Pharmacy, Sanata Dharma University, YogyakartaFaculty of Pharmacy, Sanata Dharma University, YogyakartaFaculty of Pharmacy, Sanata Dharma University, YogyakartaFaculty of Pharmacy, Sanata Dharma University, YogyakartaFaculty of Pharmacy, Sanata Dharma University, YogyakartaCardiovascular disease is the highest cause of death with total of 17.5 million deaths in the world. Nowadays there have beenexists many methods to calculate the risk of cardiovascular disease within the next 10 years, 5 of them are Framingham Risk Score (FRS) BMI and Cholesterol, Pooled Cohort Equations (PCE), CV Risk Calculator, and Systematic Coronary Risk Evaluation (SCORE). The aim of this study waiss to compare the 5 methods of 10-year risk of cardiovascular disease based on mean values, risk categories, and statin recommendation. This observational analytic study was done with cross-sectional design. There were 169 respondents in Sleman, Yogyakarta who participated to this study. Normality of risk measurement data was performed using Kolmogorov-Smirnov test and comparative test was performed using Repeated ANOVA. Both proportion of risk categorization and statin therapy was calculated using the Marginal Homogeneity test. The average risk of FRS (BMI and Cholesterol), PCE, CV Risk Calculator, and SCORE were 14,6±11,7% (medium risk), 13,3±11,3% (medium risk), 6,8±6,4% (medium risk), 6,8±6,4% (medium risk), and 2,6±3,5% (medium risk). There were significant differences from the comparison between among methods on mean values and risk categories (p <0.01), except on PCE with FRS BMI (p=0.11) and PCE with CVRiskcalculator (p = 1.00). Comparison of statin therapy recommendation among FRS Cholesterol with PCE, FRS Cholesterol with SCORE, and PCE with FRS BMI methods showed significant differences (p <0.01), whereas FRS Cholesterol with FRS BMI and PCE with SCORE were not significantly different (p = 0,06 and p = 0,05).https://jurnal.ugm.ac.id/jmpf/article/view/34469Risiko Penyakit KardiovaskulerFramingham Risk Score BMIFramingham Risk Score CholesterolPooled Cohort Equations (PCE)CV Risk CalculatorSystematic Coronary Risk Estimation (SCORE) |
| spellingShingle | Clarentia Dwivani Herlina Herlina Karina Harijadi Budianto Budianto Rita Suhadi Five Methods Comparison of 10 Years Cardiovascular Disease Risk Estimation in the Community in Sleman-Yogyakarta Jurnal Manajemen dan Pelayanan Farmasi Risiko Penyakit Kardiovaskuler Framingham Risk Score BMI Framingham Risk Score Cholesterol Pooled Cohort Equations (PCE) CV Risk Calculator Systematic Coronary Risk Estimation (SCORE) |
| title | Five Methods Comparison of 10 Years Cardiovascular Disease Risk Estimation in the Community in Sleman-Yogyakarta |
| title_full | Five Methods Comparison of 10 Years Cardiovascular Disease Risk Estimation in the Community in Sleman-Yogyakarta |
| title_fullStr | Five Methods Comparison of 10 Years Cardiovascular Disease Risk Estimation in the Community in Sleman-Yogyakarta |
| title_full_unstemmed | Five Methods Comparison of 10 Years Cardiovascular Disease Risk Estimation in the Community in Sleman-Yogyakarta |
| title_short | Five Methods Comparison of 10 Years Cardiovascular Disease Risk Estimation in the Community in Sleman-Yogyakarta |
| title_sort | five methods comparison of 10 years cardiovascular disease risk estimation in the community in sleman yogyakarta |
| topic | Risiko Penyakit Kardiovaskuler Framingham Risk Score BMI Framingham Risk Score Cholesterol Pooled Cohort Equations (PCE) CV Risk Calculator Systematic Coronary Risk Estimation (SCORE) |
| url | https://jurnal.ugm.ac.id/jmpf/article/view/34469 |
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