Development of a high-performance liquid chromatography for analysis of corosolic acid in Lagerstroemia species and their hypoglycemic potentials
Worldwide people suffer from metabolic syndrome and its complications. For these conditions, functional foods are becoming more important. We aimed to determine the amounts of corosolic acid in Lagerstroemia species and their αglucosidase inhibitory potency. In addition, we developed a new source o...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Prince of Songkla University
2020-04-01
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| Series: | Songklanakarin Journal of Science and Technology (SJST) |
| Subjects: | |
| Online Access: | https://rdo.psu.ac.th/sjstweb/journal/42-2/10.pdf |
| _version_ | 1818776796407005184 |
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| author | Gorawit Yusakul Paritad Saensom Nattapol Mitsantia Chattarika Pengdee Waraporn Putalun |
| author_facet | Gorawit Yusakul Paritad Saensom Nattapol Mitsantia Chattarika Pengdee Waraporn Putalun |
| author_sort | Gorawit Yusakul |
| collection | DOAJ |
| description | Worldwide people suffer from metabolic syndrome and its complications. For these conditions, functional foods are
becoming more important. We aimed to determine the amounts of corosolic acid in Lagerstroemia species and their αglucosidase inhibitory potency. In addition, we developed a new source of corosolic acid using the plant tissue culture technique.
The HPLC-UV method was reliable and applicable for corosolic acid determination of the Lagerstroemia species. Although the
corosolic acid standardized extract is usually prepared using L. speciosa, our results revealed that L. macrocarpa and L. loudonii
contained much higher amounts of corosolic acid. In addition, the established callus culture of L. speciosa produced corosolic
acid with higher content than their parental L. speciosa mature leaves. The corosolic contents in these samples were also in
agreement with α-glucosidase inhibitory activity. Therefore, this method is worthy of antidiabetic standardization of Lagerstroemia derived materials. |
| first_indexed | 2024-12-18T11:18:37Z |
| format | Article |
| id | doaj.art-2488dc7f0fe54c80afa17f68cf26bc1d |
| institution | Directory Open Access Journal |
| issn | 0125-3395 |
| language | English |
| last_indexed | 2024-12-18T11:18:37Z |
| publishDate | 2020-04-01 |
| publisher | Prince of Songkla University |
| record_format | Article |
| series | Songklanakarin Journal of Science and Technology (SJST) |
| spelling | doaj.art-2488dc7f0fe54c80afa17f68cf26bc1d2022-12-21T21:09:52ZengPrince of Songkla UniversitySongklanakarin Journal of Science and Technology (SJST)0125-33952020-04-0142231432010.14456/sjst-psu.2020.41Development of a high-performance liquid chromatography for analysis of corosolic acid in Lagerstroemia species and their hypoglycemic potentialsGorawit Yusakul0Paritad Saensom1Nattapol Mitsantia2Chattarika Pengdee3Waraporn Putalun4School of Pharmacy, Walailak University, Tha Sala, Nakhon Si Thammarat, 80160 Thailand Faculty of Pharmaceutical Sciences, Khon Kaen University, Mueang, Khon Kaen, 40002 Thailand Faculty of Pharmaceutical Sciences, Khon Kaen University, Mueang, Khon Kaen, 40002 Thailand Faculty of Pharmaceutical Sciences, Khon Kaen University, Mueang, Khon Kaen, 40002 Thailand Faculty of Pharmaceutical Sciences, Khon Kaen University, Mueang, Khon Kaen, 40002 ThailandWorldwide people suffer from metabolic syndrome and its complications. For these conditions, functional foods are becoming more important. We aimed to determine the amounts of corosolic acid in Lagerstroemia species and their αglucosidase inhibitory potency. In addition, we developed a new source of corosolic acid using the plant tissue culture technique. The HPLC-UV method was reliable and applicable for corosolic acid determination of the Lagerstroemia species. Although the corosolic acid standardized extract is usually prepared using L. speciosa, our results revealed that L. macrocarpa and L. loudonii contained much higher amounts of corosolic acid. In addition, the established callus culture of L. speciosa produced corosolic acid with higher content than their parental L. speciosa mature leaves. The corosolic contents in these samples were also in agreement with α-glucosidase inhibitory activity. Therefore, this method is worthy of antidiabetic standardization of Lagerstroemia derived materials.https://rdo.psu.ac.th/sjstweb/journal/42-2/10.pdflagerstroemiacorosolic acidhplcα-glucosidase inhibitiondiabetes |
| spellingShingle | Gorawit Yusakul Paritad Saensom Nattapol Mitsantia Chattarika Pengdee Waraporn Putalun Development of a high-performance liquid chromatography for analysis of corosolic acid in Lagerstroemia species and their hypoglycemic potentials Songklanakarin Journal of Science and Technology (SJST) lagerstroemia corosolic acid hplc α-glucosidase inhibition diabetes |
| title | Development of a high-performance liquid chromatography for analysis of corosolic acid in Lagerstroemia species and their hypoglycemic potentials |
| title_full | Development of a high-performance liquid chromatography for analysis of corosolic acid in Lagerstroemia species and their hypoglycemic potentials |
| title_fullStr | Development of a high-performance liquid chromatography for analysis of corosolic acid in Lagerstroemia species and their hypoglycemic potentials |
| title_full_unstemmed | Development of a high-performance liquid chromatography for analysis of corosolic acid in Lagerstroemia species and their hypoglycemic potentials |
| title_short | Development of a high-performance liquid chromatography for analysis of corosolic acid in Lagerstroemia species and their hypoglycemic potentials |
| title_sort | development of a high performance liquid chromatography for analysis of corosolic acid in lagerstroemia species and their hypoglycemic potentials |
| topic | lagerstroemia corosolic acid hplc α-glucosidase inhibition diabetes |
| url | https://rdo.psu.ac.th/sjstweb/journal/42-2/10.pdf |
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