Renin profiling predicts neurohormonal response to sacubitril/valsartan

Renin profiling predicts neurohormonal response to sacubitril/valsartan

Abstract Aims Clinical trials and observational cohorts show that beneficial effects of sacubitril/valsartan are less strong in an appreciable proportion of patients with heart failure with reduced ejection fraction (HFrEF). Lower blood pressure and impaired renal function predict suboptimal sacubit...

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Bibliographic Details
Main Authors: Giuseppe Vergaro, Paolo Sciarrone, Concetta Prontera, Silvia Masotti, Veronica Musetti, Alessandro Valleggi, Alberto Giannoni, Michele Senni, Michele Emdin, Claudio Passino
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:ESC Heart Failure
Subjects:
Heart failure
Sacubitril/valsartan
Renin
Natriuretic peptides
Online Access:https://doi.org/10.1002/ehf2.13085

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