Sympathomimetic-Induced Hyperthermia and Hyponatremia: A Simulation Case for Emergency Medicine Residents

Introduction MDMA (3,4-methylenedioxymethamphetamine) is a popular drug of abuse associated with a variety of clinical manifestations. There are a number of life-threatening sequelae, including, but not limited to, agitated delirium, cardiac dysrhythmias, and hyperthermia. Similar to other substance...

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Main Authors: Ashlea Winfield, Elizabeth Black, Michelle Sergel
Format: Article
Language:English
Published: Association of American Medical Colleges 2021-01-01
Series:MedEdPORTAL
Subjects:
Online Access:http://www.mededportal.org/doi/10.15766/mep_2374-8265.11092
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author Ashlea Winfield
Elizabeth Black
Michelle Sergel
author_facet Ashlea Winfield
Elizabeth Black
Michelle Sergel
author_sort Ashlea Winfield
collection DOAJ
description Introduction MDMA (3,4-methylenedioxymethamphetamine) is a popular drug of abuse associated with a variety of clinical manifestations. There are a number of life-threatening sequelae, including, but not limited to, agitated delirium, cardiac dysrhythmias, and hyperthermia. Similar to other substances that cause sympathomimetic toxidromes, MDMA also induces a syndrome of inappropriate antidiuretic hormone secretion-like state resulting in hyponatremia. The management of hyperthermia is of particular importance, as time to correction, particularly at temperatures greater than 106 °F, is directly associated with increased risk of morbidity and mortality. Methods We created a simulation-based intervention to address and improve clinical skills relating to the management of MDMA intoxication. The scenario used a simulated patient to teach emergency medicine residents how to properly diagnose sympathomimetic toxicity and manage resultant hyperthermia and hyponatremia with cooling measures and appropriate fluid administration. Learners participated in a debrief session and were given an anonymous survey to assess their perceived knowledge. The case was performed as part of monthly emergency medicine resident didactics. Results Eighteen learners took part in the case, with a 100% response rate. All participants agreed that the scenario increased their knowledge of cooling methods in severe hyperthermia, particularly whole-body packing. Eighty-nine percent (n = 16) reported that the scenario changed their practice patterns. Discussion This simulated scenario requires minimal resources and can be instituted with emergency medicine residents from all levels of training. The scenario achieved its primary goal of improving residents' perceived knowledge of cooling measures in severe hyperthermia.
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spelling doaj.art-24901a0a312943eda973208c2958158f2022-12-21T19:55:59ZengAssociation of American Medical CollegesMedEdPORTAL2374-82652021-01-011710.15766/mep_2374-8265.11092Sympathomimetic-Induced Hyperthermia and Hyponatremia: A Simulation Case for Emergency Medicine ResidentsAshlea Winfield0Elizabeth Black1Michelle Sergel2Simulation Fellow, Department of Emergency Medicine, Cook County HealthToxicology Fellow, Department of Emergency Medicine, Cook County HealthDirector of Cook County Simulation Center, Department of Emergency Medicine, Cook County Health; Co-Executive Director, Rush Center for Clinical Skills and SimulationIntroduction MDMA (3,4-methylenedioxymethamphetamine) is a popular drug of abuse associated with a variety of clinical manifestations. There are a number of life-threatening sequelae, including, but not limited to, agitated delirium, cardiac dysrhythmias, and hyperthermia. Similar to other substances that cause sympathomimetic toxidromes, MDMA also induces a syndrome of inappropriate antidiuretic hormone secretion-like state resulting in hyponatremia. The management of hyperthermia is of particular importance, as time to correction, particularly at temperatures greater than 106 °F, is directly associated with increased risk of morbidity and mortality. Methods We created a simulation-based intervention to address and improve clinical skills relating to the management of MDMA intoxication. The scenario used a simulated patient to teach emergency medicine residents how to properly diagnose sympathomimetic toxicity and manage resultant hyperthermia and hyponatremia with cooling measures and appropriate fluid administration. Learners participated in a debrief session and were given an anonymous survey to assess their perceived knowledge. The case was performed as part of monthly emergency medicine resident didactics. Results Eighteen learners took part in the case, with a 100% response rate. All participants agreed that the scenario increased their knowledge of cooling methods in severe hyperthermia, particularly whole-body packing. Eighty-nine percent (n = 16) reported that the scenario changed their practice patterns. Discussion This simulated scenario requires minimal resources and can be instituted with emergency medicine residents from all levels of training. The scenario achieved its primary goal of improving residents' perceived knowledge of cooling measures in severe hyperthermia.http://www.mededportal.org/doi/10.15766/mep_2374-8265.11092Sympathomimetic ToxidromeMDMA3,4-Methylenedioxymethamphetamine (MDMA)HyperthermiaSymptomatic HyponatremiaEmergency Medicine
spellingShingle Ashlea Winfield
Elizabeth Black
Michelle Sergel
Sympathomimetic-Induced Hyperthermia and Hyponatremia: A Simulation Case for Emergency Medicine Residents
MedEdPORTAL
Sympathomimetic Toxidrome
MDMA
3,4-Methylenedioxymethamphetamine (MDMA)
Hyperthermia
Symptomatic Hyponatremia
Emergency Medicine
title Sympathomimetic-Induced Hyperthermia and Hyponatremia: A Simulation Case for Emergency Medicine Residents
title_full Sympathomimetic-Induced Hyperthermia and Hyponatremia: A Simulation Case for Emergency Medicine Residents
title_fullStr Sympathomimetic-Induced Hyperthermia and Hyponatremia: A Simulation Case for Emergency Medicine Residents
title_full_unstemmed Sympathomimetic-Induced Hyperthermia and Hyponatremia: A Simulation Case for Emergency Medicine Residents
title_short Sympathomimetic-Induced Hyperthermia and Hyponatremia: A Simulation Case for Emergency Medicine Residents
title_sort sympathomimetic induced hyperthermia and hyponatremia a simulation case for emergency medicine residents
topic Sympathomimetic Toxidrome
MDMA
3,4-Methylenedioxymethamphetamine (MDMA)
Hyperthermia
Symptomatic Hyponatremia
Emergency Medicine
url http://www.mededportal.org/doi/10.15766/mep_2374-8265.11092
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