Predictive value of the systemic immune inflammation (SII) index for stroke‐associated pneumonia
Abstract Objective To investigate the predictive value of the systemic immune inflammation (SII) index on the occurrence of stroke‐associated pneumonia (SAP) in patients with acute stroke. Methods Data of patients with or without a previous history of pulmonary who visited the First Affiliated Hospi...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-12-01
|
| Series: | Brain and Behavior |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/brb3.3302 |
| _version_ | 1797336346682982400 |
|---|---|
| author | Zhanhang Cui Sai Kuang Xiaorong Yang Ying Wang Shanshan Gu Hongyu Li Huibin Chen Yanbing Han Haimei Sun |
| author_facet | Zhanhang Cui Sai Kuang Xiaorong Yang Ying Wang Shanshan Gu Hongyu Li Huibin Chen Yanbing Han Haimei Sun |
| author_sort | Zhanhang Cui |
| collection | DOAJ |
| description | Abstract Objective To investigate the predictive value of the systemic immune inflammation (SII) index on the occurrence of stroke‐associated pneumonia (SAP) in patients with acute stroke. Methods Data of patients with or without a previous history of pulmonary who visited the First Affiliated Hospital of Kunming Medical University within 24 h of the onset of stroke were collected between January 2017 and December 2019. Patient's demographic data, stroke type, past medical history, National Institutes of Health Stroke Scale score, Glasgow Coma score, and laboratory tests were collected. Logistic regression models and receiver‐operating characteristic (ROC) curves were used to investigate the predictive value of SII for the development of SAP in patients with stroke. Results We included 395 patients with acute stroke, with a mean age of 63.89 ± 13.42 years, of whom 340 (86.1%) had ischemic stroke, and 55 (13.9%) had hemorrhagic stroke. Out of 395, 113 (28.6%) had SAP and 282 (71.4%) did not, and the SII level in the SAP group was higher than that of the non‐SAP group (p < .05). Logistic regression analysis of patients with stroke showed that higher SII was a risk factor for SAP in patients with stroke (per 100 units, HR = 1.081, 95% CI: 1.035–1.130, p < .001), and tertile grouping of SII showed that the risk of SAP was 5.059 times higher in the SIIQ3 group than in the SIIQ1 group (95% CI: 2.061–12.418, p < .001). ROC curve analysis indicated that the SII index had predictive value for the occurrence of SAP in patients with stroke, with an area under the curve of 0.752 (95% CI: 0.698–0.806). When the cutoff value was 861.01, the SII predicted SAP in patients with stroke with a sensitivity of 61.9% and a specificity of 76.2%. Conclusion Higher SII is an independent risk factor for the development of SAP in patients with stroke and has some predictive value for the development of SAP. |
| first_indexed | 2024-03-08T08:53:03Z |
| format | Article |
| id | doaj.art-24957719cff74bd7ae58bc841ccf8b5f |
| institution | Directory Open Access Journal |
| issn | 2162-3279 |
| language | English |
| last_indexed | 2024-03-08T08:53:03Z |
| publishDate | 2023-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | Brain and Behavior |
| spelling | doaj.art-24957719cff74bd7ae58bc841ccf8b5f2024-02-01T07:45:36ZengWileyBrain and Behavior2162-32792023-12-011312n/an/a10.1002/brb3.3302Predictive value of the systemic immune inflammation (SII) index for stroke‐associated pneumoniaZhanhang Cui0Sai Kuang1Xiaorong Yang2Ying Wang3Shanshan Gu4Hongyu Li5Huibin Chen6Yanbing Han7Haimei Sun8School of Public Health Kunming Medical University Kunming, Yunnan Province ChinaSchool of Public Health Kunming Medical University Kunming, Yunnan Province ChinaDepartment of Critical Care Medicine First Affiliated Hospital of Kunming Medical University Kunming, Yunnan Province ChinaDepartment of Critical Care Medicine First Affiliated Hospital of Kunming Medical University Kunming, Yunnan Province ChinaDepartment of Critical Care Medicine First Affiliated Hospital of Kunming Medical University Kunming, Yunnan Province ChinaDepartment of Critical Care Medicine First Affiliated Hospital of Kunming Medical University Kunming, Yunnan Province ChinaDepartment of Critical Care Medicine First Affiliated Hospital of Kunming Medical University Kunming, Yunnan Province ChinaDepartment of Neurology First Affiliated Hospital of Kunming Medical University Kunming, Yunnan Province ChinaDepartment of Neurology First Affiliated Hospital of Kunming Medical University Kunming, Yunnan Province ChinaAbstract Objective To investigate the predictive value of the systemic immune inflammation (SII) index on the occurrence of stroke‐associated pneumonia (SAP) in patients with acute stroke. Methods Data of patients with or without a previous history of pulmonary who visited the First Affiliated Hospital of Kunming Medical University within 24 h of the onset of stroke were collected between January 2017 and December 2019. Patient's demographic data, stroke type, past medical history, National Institutes of Health Stroke Scale score, Glasgow Coma score, and laboratory tests were collected. Logistic regression models and receiver‐operating characteristic (ROC) curves were used to investigate the predictive value of SII for the development of SAP in patients with stroke. Results We included 395 patients with acute stroke, with a mean age of 63.89 ± 13.42 years, of whom 340 (86.1%) had ischemic stroke, and 55 (13.9%) had hemorrhagic stroke. Out of 395, 113 (28.6%) had SAP and 282 (71.4%) did not, and the SII level in the SAP group was higher than that of the non‐SAP group (p < .05). Logistic regression analysis of patients with stroke showed that higher SII was a risk factor for SAP in patients with stroke (per 100 units, HR = 1.081, 95% CI: 1.035–1.130, p < .001), and tertile grouping of SII showed that the risk of SAP was 5.059 times higher in the SIIQ3 group than in the SIIQ1 group (95% CI: 2.061–12.418, p < .001). ROC curve analysis indicated that the SII index had predictive value for the occurrence of SAP in patients with stroke, with an area under the curve of 0.752 (95% CI: 0.698–0.806). When the cutoff value was 861.01, the SII predicted SAP in patients with stroke with a sensitivity of 61.9% and a specificity of 76.2%. Conclusion Higher SII is an independent risk factor for the development of SAP in patients with stroke and has some predictive value for the development of SAP.https://doi.org/10.1002/brb3.3302acute strokepredictive valuestroke‐associated pneumoniasystemic immune inflammation index |
| spellingShingle | Zhanhang Cui Sai Kuang Xiaorong Yang Ying Wang Shanshan Gu Hongyu Li Huibin Chen Yanbing Han Haimei Sun Predictive value of the systemic immune inflammation (SII) index for stroke‐associated pneumonia Brain and Behavior acute stroke predictive value stroke‐associated pneumonia systemic immune inflammation index |
| title | Predictive value of the systemic immune inflammation (SII) index for stroke‐associated pneumonia |
| title_full | Predictive value of the systemic immune inflammation (SII) index for stroke‐associated pneumonia |
| title_fullStr | Predictive value of the systemic immune inflammation (SII) index for stroke‐associated pneumonia |
| title_full_unstemmed | Predictive value of the systemic immune inflammation (SII) index for stroke‐associated pneumonia |
| title_short | Predictive value of the systemic immune inflammation (SII) index for stroke‐associated pneumonia |
| title_sort | predictive value of the systemic immune inflammation sii index for stroke associated pneumonia |
| topic | acute stroke predictive value stroke‐associated pneumonia systemic immune inflammation index |
| url | https://doi.org/10.1002/brb3.3302 |
| work_keys_str_mv | AT zhanhangcui predictivevalueofthesystemicimmuneinflammationsiiindexforstrokeassociatedpneumonia AT saikuang predictivevalueofthesystemicimmuneinflammationsiiindexforstrokeassociatedpneumonia AT xiaorongyang predictivevalueofthesystemicimmuneinflammationsiiindexforstrokeassociatedpneumonia AT yingwang predictivevalueofthesystemicimmuneinflammationsiiindexforstrokeassociatedpneumonia AT shanshangu predictivevalueofthesystemicimmuneinflammationsiiindexforstrokeassociatedpneumonia AT hongyuli predictivevalueofthesystemicimmuneinflammationsiiindexforstrokeassociatedpneumonia AT huibinchen predictivevalueofthesystemicimmuneinflammationsiiindexforstrokeassociatedpneumonia AT yanbinghan predictivevalueofthesystemicimmuneinflammationsiiindexforstrokeassociatedpneumonia AT haimeisun predictivevalueofthesystemicimmuneinflammationsiiindexforstrokeassociatedpneumonia |