Development of machine learning models for the prediction of the skin sensitization potential of cosmetic compounds
Background To enhance the accuracy of allergen detection in cosmetic compounds, we developed a co-culture system that combines HaCaT keratinocytes (transfected with a luciferase plasmid driven by the AKR1C2 promoter) and THP-1 cells for machine learning applications. Methods Following chemical expos...
Główni autorzy: | , , , |
---|---|
Format: | Artykuł |
Język: | English |
Wydane: |
PeerJ Inc.
2024-12-01
|
Seria: | PeerJ |
Hasła przedmiotowe: | |
Dostęp online: | https://peerj.com/articles/18672.pdf |