Salivary Gland Ultrasound in Primary Sjögren’s Syndrome: Current and Future Perspectives
Michele Lorenzon,1 Erica Spina,1 Francesco Tulipano Di Franco,1 Ivan Giovannini,2 Salvatore De Vita,2 Alen Zabotti2 1Institute of Radiology, Department of Medicine, University of Udine, Udine, Italy; 2Rheumatology Clinic, Department of Medical and Biological Sciences, Azienda Sanitaria Universitaria...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2022-09-01
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| Series: | Open Access Rheumatology: Research and Reviews |
| Subjects: | |
| Online Access: | https://www.dovepress.com/salivary-gland-ultrasound-in-primary-sjgrens-syndrome-current-and-futu-peer-reviewed-fulltext-article-OARRR |
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| author | Lorenzon M Spina E Tulipano Di Franco F Giovannini I De Vita S Zabotti A |
| author_facet | Lorenzon M Spina E Tulipano Di Franco F Giovannini I De Vita S Zabotti A |
| author_sort | Lorenzon M |
| collection | DOAJ |
| description | Michele Lorenzon,1 Erica Spina,1 Francesco Tulipano Di Franco,1 Ivan Giovannini,2 Salvatore De Vita,2 Alen Zabotti2 1Institute of Radiology, Department of Medicine, University of Udine, Udine, Italy; 2Rheumatology Clinic, Department of Medical and Biological Sciences, Azienda Sanitaria Universitaria Friuli Centrale c/o University of Udine, Udine, ItalyCorrespondence: Michele Lorenzon, Institute of Radiology, Department of Medicine, University of Udine, Udine, Italy, Tel +39 0432 559232, Email michele.lorenzon@gmail.comAbstract: Salivary gland ultrasound (SGUS) is the imaging modality of choice for the assessment of parotid and submandibular gland parenchyma. Being highly effective, non-invasive and easy to perform, SGUS has become increasingly popular among specialists in assessing salivary gland (SG) abnormalities, including those commonly found in primary Sjögren’s syndrome (pSS). SGUS may be useful in the assessment of pSS and its complications, the most serious being the development of non-Hodgkin’s lymphoma (NHL). SGUS may also be useful in the characterization and differential diagnosis of diffuse and focal abnormalities commonly associated with pSS, and may act as a guide for core-needle biopsy (CNB), an established, safe, and feasible technique, which provides enough viable tissue for the diagnosis and assessment of lymphoproliferative diseases of the SG. The combination of SGUS with other tools, such as sonoelastography and artificial intelligence (AI), could further improve the usefulness of SGUS in the management of pSS. In this perspective, we summarize current and future applications of SGUS in pSS.Keywords: primary Sjögren’s syndrome, major salivary glands, ultrasound, lymphoma, core needle biopsy |
| first_indexed | 2024-04-11T10:58:23Z |
| format | Article |
| id | doaj.art-249bf9612e0e44abb016728406621b00 |
| institution | Directory Open Access Journal |
| issn | 1179-156X |
| language | English |
| last_indexed | 2024-04-11T10:58:23Z |
| publishDate | 2022-09-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Open Access Rheumatology: Research and Reviews |
| spelling | doaj.art-249bf9612e0e44abb016728406621b002022-12-22T04:28:43ZengDove Medical PressOpen Access Rheumatology: Research and Reviews1179-156X2022-09-01Volume 1414716077862Salivary Gland Ultrasound in Primary Sjögren’s Syndrome: Current and Future PerspectivesLorenzon MSpina ETulipano Di Franco FGiovannini IDe Vita SZabotti AMichele Lorenzon,1 Erica Spina,1 Francesco Tulipano Di Franco,1 Ivan Giovannini,2 Salvatore De Vita,2 Alen Zabotti2 1Institute of Radiology, Department of Medicine, University of Udine, Udine, Italy; 2Rheumatology Clinic, Department of Medical and Biological Sciences, Azienda Sanitaria Universitaria Friuli Centrale c/o University of Udine, Udine, ItalyCorrespondence: Michele Lorenzon, Institute of Radiology, Department of Medicine, University of Udine, Udine, Italy, Tel +39 0432 559232, Email michele.lorenzon@gmail.comAbstract: Salivary gland ultrasound (SGUS) is the imaging modality of choice for the assessment of parotid and submandibular gland parenchyma. Being highly effective, non-invasive and easy to perform, SGUS has become increasingly popular among specialists in assessing salivary gland (SG) abnormalities, including those commonly found in primary Sjögren’s syndrome (pSS). SGUS may be useful in the assessment of pSS and its complications, the most serious being the development of non-Hodgkin’s lymphoma (NHL). SGUS may also be useful in the characterization and differential diagnosis of diffuse and focal abnormalities commonly associated with pSS, and may act as a guide for core-needle biopsy (CNB), an established, safe, and feasible technique, which provides enough viable tissue for the diagnosis and assessment of lymphoproliferative diseases of the SG. The combination of SGUS with other tools, such as sonoelastography and artificial intelligence (AI), could further improve the usefulness of SGUS in the management of pSS. In this perspective, we summarize current and future applications of SGUS in pSS.Keywords: primary Sjögren’s syndrome, major salivary glands, ultrasound, lymphoma, core needle biopsyhttps://www.dovepress.com/salivary-gland-ultrasound-in-primary-sjgrens-syndrome-current-and-futu-peer-reviewed-fulltext-article-OARRRprimary sjögren’s syndromemajor salivary glandsultrasoundlymphomacore needle biopsy. |
| spellingShingle | Lorenzon M Spina E Tulipano Di Franco F Giovannini I De Vita S Zabotti A Salivary Gland Ultrasound in Primary Sjögren’s Syndrome: Current and Future Perspectives Open Access Rheumatology: Research and Reviews primary sjögren’s syndrome major salivary glands ultrasound lymphoma core needle biopsy. |
| title | Salivary Gland Ultrasound in Primary Sjögren’s Syndrome: Current and Future Perspectives |
| title_full | Salivary Gland Ultrasound in Primary Sjögren’s Syndrome: Current and Future Perspectives |
| title_fullStr | Salivary Gland Ultrasound in Primary Sjögren’s Syndrome: Current and Future Perspectives |
| title_full_unstemmed | Salivary Gland Ultrasound in Primary Sjögren’s Syndrome: Current and Future Perspectives |
| title_short | Salivary Gland Ultrasound in Primary Sjögren’s Syndrome: Current and Future Perspectives |
| title_sort | salivary gland ultrasound in primary sj ouml gren rsquo s syndrome current and future perspectives |
| topic | primary sjögren’s syndrome major salivary glands ultrasound lymphoma core needle biopsy. |
| url | https://www.dovepress.com/salivary-gland-ultrasound-in-primary-sjgrens-syndrome-current-and-futu-peer-reviewed-fulltext-article-OARRR |
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