Prokaryotic ncRNAs: Master regulators of gene expression

ncRNA plays a very pivotal role in various biological activities ranging from gene regulation to controlling important developmental networks. It is imperative to note that this small molecule is not only present in all three domains of cellular life, but is an important modulator of gene regulation...

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Main Authors: Rajib Majumder, Sanmitra Ghosh, Arpita Das, Manoj Kumar Singh, Saikat Samanta, Abinit Saha, Rudra P. Saha
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Current Research in Pharmacology and Drug Discovery
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590257122000566
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author Rajib Majumder
Sanmitra Ghosh
Arpita Das
Manoj Kumar Singh
Saikat Samanta
Abinit Saha
Rudra P. Saha
author_facet Rajib Majumder
Sanmitra Ghosh
Arpita Das
Manoj Kumar Singh
Saikat Samanta
Abinit Saha
Rudra P. Saha
author_sort Rajib Majumder
collection DOAJ
description ncRNA plays a very pivotal role in various biological activities ranging from gene regulation to controlling important developmental networks. It is imperative to note that this small molecule is not only present in all three domains of cellular life, but is an important modulator of gene regulation too in all these domains. In this review, we discussed various aspects of ncRNA biology, especially their role in bacteria. The last two decades of scientific research have proved that this molecule plays an important role in the modulation of various regulatory pathways in bacteria including the adaptive immune system and gene regulation. It is also very surprising to note that this small molecule is also employed in various processes related to the pathogenicity of virulent microorganisms.
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spelling doaj.art-249f7b030c6f4472ac47e591c82e7e192022-12-22T04:22:28ZengElsevierCurrent Research in Pharmacology and Drug Discovery2590-25712022-01-013100136Prokaryotic ncRNAs: Master regulators of gene expressionRajib Majumder0Sanmitra Ghosh1Arpita Das2Manoj Kumar Singh3Saikat Samanta4Abinit Saha5Rudra P. Saha6Department of Biotechnology, School of Life Science & Biotechnology, Adamas University, Kolkata, 700126, IndiaDepartment of Biological Sciences, School of Life Science & Biotechnology, Adamas University, Kolkata, 700126, IndiaDepartment of Biotechnology, School of Life Science & Biotechnology, Adamas University, Kolkata, 700126, IndiaDepartment of Biotechnology, School of Life Science & Biotechnology, Adamas University, Kolkata, 700126, IndiaDepartment of Biotechnology, School of Life Science & Biotechnology, Adamas University, Kolkata, 700126, IndiaDepartment of Biotechnology, School of Life Science & Biotechnology, Adamas University, Kolkata, 700126, India; Corresponding authors.Department of Biotechnology, School of Life Science & Biotechnology, Adamas University, Kolkata, 700126, India; Corresponding authors.ncRNA plays a very pivotal role in various biological activities ranging from gene regulation to controlling important developmental networks. It is imperative to note that this small molecule is not only present in all three domains of cellular life, but is an important modulator of gene regulation too in all these domains. In this review, we discussed various aspects of ncRNA biology, especially their role in bacteria. The last two decades of scientific research have proved that this molecule plays an important role in the modulation of various regulatory pathways in bacteria including the adaptive immune system and gene regulation. It is also very surprising to note that this small molecule is also employed in various processes related to the pathogenicity of virulent microorganisms.http://www.sciencedirect.com/science/article/pii/S2590257122000566ncRNAProkaryotic ncRNABacterial ncRNAncRNA biologyGene regulationCRISPR
spellingShingle Rajib Majumder
Sanmitra Ghosh
Arpita Das
Manoj Kumar Singh
Saikat Samanta
Abinit Saha
Rudra P. Saha
Prokaryotic ncRNAs: Master regulators of gene expression
Current Research in Pharmacology and Drug Discovery
ncRNA
Prokaryotic ncRNA
Bacterial ncRNA
ncRNA biology
Gene regulation
CRISPR
title Prokaryotic ncRNAs: Master regulators of gene expression
title_full Prokaryotic ncRNAs: Master regulators of gene expression
title_fullStr Prokaryotic ncRNAs: Master regulators of gene expression
title_full_unstemmed Prokaryotic ncRNAs: Master regulators of gene expression
title_short Prokaryotic ncRNAs: Master regulators of gene expression
title_sort prokaryotic ncrnas master regulators of gene expression
topic ncRNA
Prokaryotic ncRNA
Bacterial ncRNA
ncRNA biology
Gene regulation
CRISPR
url http://www.sciencedirect.com/science/article/pii/S2590257122000566
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