Just breathe: a review of sex and gender in chronic lung disease
Chronic lung diseases are the third leading cause of death worldwide and are increasing in prevalence over time. Although much of our traditional understanding of health and disease is derived from study of the male of the species – be it animal or human – there is increasing evidence that sex and g...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
European Respiratory Society
2022-01-01
|
| Series: | European Respiratory Review |
| Online Access: | http://err.ersjournals.com/content/31/163/210111.full |
| _version_ | 1811313066265018368 |
|---|---|
| author | Ranjani Somayaji James D. Chalmers |
| author_facet | Ranjani Somayaji James D. Chalmers |
| author_sort | Ranjani Somayaji |
| collection | DOAJ |
| description | Chronic lung diseases are the third leading cause of death worldwide and are increasing in prevalence over time. Although much of our traditional understanding of health and disease is derived from study of the male of the species – be it animal or human – there is increasing evidence that sex and gender contribute to differences in disease risk, prevalence, presentation, severity, treatment approach, response and outcomes. Chronic obstructive pulmonary disease, asthma and bronchiectasis represent the most prevalent and studied chronic lung diseases and have key sex- and gender-based differences which are critical to consider and incorporate into clinical and research approaches. Mechanistic differences present opportunities for therapeutic development whereas behavioural and clinical differences on the part of patients and providers present opportunities for greater education and understanding at multiple levels. In this review, we seek to summarise the sex- and gender-based differences in key chronic lung diseases and outline the clinical and research implications for stakeholders. |
| first_indexed | 2024-04-13T10:47:40Z |
| format | Article |
| id | doaj.art-24a0cb0005ad4610b629507a137d6802 |
| institution | Directory Open Access Journal |
| issn | 0905-9180 1600-0617 |
| language | English |
| last_indexed | 2024-04-13T10:47:40Z |
| publishDate | 2022-01-01 |
| publisher | European Respiratory Society |
| record_format | Article |
| series | European Respiratory Review |
| spelling | doaj.art-24a0cb0005ad4610b629507a137d68022022-12-22T02:49:44ZengEuropean Respiratory SocietyEuropean Respiratory Review0905-91801600-06172022-01-013116310.1183/16000617.0111-20210111-2021Just breathe: a review of sex and gender in chronic lung diseaseRanjani Somayaji0James D. Chalmers1 Dept of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Canada Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK Chronic lung diseases are the third leading cause of death worldwide and are increasing in prevalence over time. Although much of our traditional understanding of health and disease is derived from study of the male of the species – be it animal or human – there is increasing evidence that sex and gender contribute to differences in disease risk, prevalence, presentation, severity, treatment approach, response and outcomes. Chronic obstructive pulmonary disease, asthma and bronchiectasis represent the most prevalent and studied chronic lung diseases and have key sex- and gender-based differences which are critical to consider and incorporate into clinical and research approaches. Mechanistic differences present opportunities for therapeutic development whereas behavioural and clinical differences on the part of patients and providers present opportunities for greater education and understanding at multiple levels. In this review, we seek to summarise the sex- and gender-based differences in key chronic lung diseases and outline the clinical and research implications for stakeholders.http://err.ersjournals.com/content/31/163/210111.full |
| spellingShingle | Ranjani Somayaji James D. Chalmers Just breathe: a review of sex and gender in chronic lung disease European Respiratory Review |
| title | Just breathe: a review of sex and gender in chronic lung disease |
| title_full | Just breathe: a review of sex and gender in chronic lung disease |
| title_fullStr | Just breathe: a review of sex and gender in chronic lung disease |
| title_full_unstemmed | Just breathe: a review of sex and gender in chronic lung disease |
| title_short | Just breathe: a review of sex and gender in chronic lung disease |
| title_sort | just breathe a review of sex and gender in chronic lung disease |
| url | http://err.ersjournals.com/content/31/163/210111.full |
| work_keys_str_mv | AT ranjanisomayaji justbreatheareviewofsexandgenderinchroniclungdisease AT jamesdchalmers justbreatheareviewofsexandgenderinchroniclungdisease |