The relationship between left ventricular dilation and right ventricular diastolic function in children with a patent ductus arteriosus
The impact of a dilated left ventricular (LV) on right ventricular (RV) diastolic function has not been investigated. We hypothesized that in patients with a patent ductus arteriosus (PDA), LV dilation causes elevation of the RV end-diastolic pressure (RVEDP) through ventricular-ventricular interact...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Annals of Pediatric Cardiology |
| Subjects: | |
| Online Access: | http://www.annalspc.com/article.asp?issn=0974-2069;year=2023;volume=16;issue=1;spage=41;epage=44;aulast=Miller |
| _version_ | 1797824493173866496 |
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| author | Cole Miller William Anderson Joseph A Paolillo Matthew C Schwartz |
| author_facet | Cole Miller William Anderson Joseph A Paolillo Matthew C Schwartz |
| author_sort | Cole Miller |
| collection | DOAJ |
| description | The impact of a dilated left ventricular (LV) on right ventricular (RV) diastolic function has not been investigated. We hypothesized that in patients with a patent ductus arteriosus (PDA), LV dilation causes elevation of the RV end-diastolic pressure (RVEDP) through ventricular-ventricular interaction. We identified patients' ages 6 months to 18 years who underwent transcatheter PDA closure at our center from 2010 to 2019. One hundred and thirteen patients were included with a median age of 3 years (0.5–18). The median LV end-diastolic dimension (LVEDD) Z-score was 1.6 (−1.4–6.3). RVEDP was positively associated with RV systolic pressure (0.38, P < 0.01), ratio of pulmonary artery/aortic systolic pressure (0.4, P < 0.01), and pulmonary capillary wedge pressure (0.71, P < 0.01). RVEDP was not associated with LVEDD Z-score (0.03, P = 0.74). In children with a PDA, RVEDP was not associated with LV dilation, but was positively associated with RV systolic pressure. |
| first_indexed | 2024-03-13T10:39:48Z |
| format | Article |
| id | doaj.art-24a5fc0d153841bd9f1ef24fe7ff1c33 |
| institution | Directory Open Access Journal |
| issn | 0974-2069 |
| language | English |
| last_indexed | 2024-03-13T10:39:48Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Pediatric Cardiology |
| spelling | doaj.art-24a5fc0d153841bd9f1ef24fe7ff1c332023-05-18T04:58:41ZengWolters Kluwer Medknow PublicationsAnnals of Pediatric Cardiology0974-20692023-01-01161414410.4103/apc.apc_84_22The relationship between left ventricular dilation and right ventricular diastolic function in children with a patent ductus arteriosusCole MillerWilliam AndersonJoseph A PaolilloMatthew C SchwartzThe impact of a dilated left ventricular (LV) on right ventricular (RV) diastolic function has not been investigated. We hypothesized that in patients with a patent ductus arteriosus (PDA), LV dilation causes elevation of the RV end-diastolic pressure (RVEDP) through ventricular-ventricular interaction. We identified patients' ages 6 months to 18 years who underwent transcatheter PDA closure at our center from 2010 to 2019. One hundred and thirteen patients were included with a median age of 3 years (0.5–18). The median LV end-diastolic dimension (LVEDD) Z-score was 1.6 (−1.4–6.3). RVEDP was positively associated with RV systolic pressure (0.38, P < 0.01), ratio of pulmonary artery/aortic systolic pressure (0.4, P < 0.01), and pulmonary capillary wedge pressure (0.71, P < 0.01). RVEDP was not associated with LVEDD Z-score (0.03, P = 0.74). In children with a PDA, RVEDP was not associated with LV dilation, but was positively associated with RV systolic pressure.http://www.annalspc.com/article.asp?issn=0974-2069;year=2023;volume=16;issue=1;spage=41;epage=44;aulast=Millerend-diastolic pressurehemodynamicspatent ductus arteriosusright ventricular function |
| spellingShingle | Cole Miller William Anderson Joseph A Paolillo Matthew C Schwartz The relationship between left ventricular dilation and right ventricular diastolic function in children with a patent ductus arteriosus Annals of Pediatric Cardiology end-diastolic pressure hemodynamics patent ductus arteriosus right ventricular function |
| title | The relationship between left ventricular dilation and right ventricular diastolic function in children with a patent ductus arteriosus |
| title_full | The relationship between left ventricular dilation and right ventricular diastolic function in children with a patent ductus arteriosus |
| title_fullStr | The relationship between left ventricular dilation and right ventricular diastolic function in children with a patent ductus arteriosus |
| title_full_unstemmed | The relationship between left ventricular dilation and right ventricular diastolic function in children with a patent ductus arteriosus |
| title_short | The relationship between left ventricular dilation and right ventricular diastolic function in children with a patent ductus arteriosus |
| title_sort | relationship between left ventricular dilation and right ventricular diastolic function in children with a patent ductus arteriosus |
| topic | end-diastolic pressure hemodynamics patent ductus arteriosus right ventricular function |
| url | http://www.annalspc.com/article.asp?issn=0974-2069;year=2023;volume=16;issue=1;spage=41;epage=44;aulast=Miller |
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