Cystic Kidney Diseases From the Adult Nephrologist’s Point of View
Cystic kidney diseases affect patients of all age groups with the onset spanning from prenatal disease to late adulthood. Autosomal-dominant polycystic kidney disease (ADPKD) is by far the most common renal cystic disease. However, there are various cystic kidney diseases, the onset of which occurs...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2018-03-01
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| Series: | Frontiers in Pediatrics |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/article/10.3389/fped.2018.00065/full |
| _version_ | 1819238274530541568 |
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| author | Roman-Ulrich Müller Thomas Benzing |
| author_facet | Roman-Ulrich Müller Thomas Benzing |
| author_sort | Roman-Ulrich Müller |
| collection | DOAJ |
| description | Cystic kidney diseases affect patients of all age groups with the onset spanning from prenatal disease to late adulthood. Autosomal-dominant polycystic kidney disease (ADPKD) is by far the most common renal cystic disease. However, there are various cystic kidney diseases, the onset of which occurs at different times in life and depends on the type of the disease and the causative genes involved. When genetic kidney diseases are discussed in the adult setting this view is usually limited on autosomal-dominant kidney disease, the most frequent genetic disorder causing adult onset ESRD. Other diseases—such as autosomal-recessive polycystic kidney disease—are often being viewed as a disorder only important in pediatric nephrology. However, more recent data has revealed that, despite clear age peaks of onset for each disorder, all of them can also show highly variable phenotypes with classical adult onset genetic diseases being of importance in pediatrics and vice versa. Furthermore, the affected children need to be seen by adult nephrologists in the long term after transition, requiring knowledge on the underlying pediatric disease, potential extrarenal manifestations, and genetic counseling. Consequently, the view on these diseases should be widened on both ends. Close interaction between pediatric and adult nephrology is key to appropriate care of patients suffering from genetic kidney disease to profit from each other’s experience. |
| first_indexed | 2024-12-23T13:33:37Z |
| format | Article |
| id | doaj.art-24a914dcf62846dc85947bcd0ee50b37 |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-12-23T13:33:37Z |
| publishDate | 2018-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-24a914dcf62846dc85947bcd0ee50b372022-12-21T17:45:05ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602018-03-01610.3389/fped.2018.00065337027Cystic Kidney Diseases From the Adult Nephrologist’s Point of ViewRoman-Ulrich MüllerThomas BenzingCystic kidney diseases affect patients of all age groups with the onset spanning from prenatal disease to late adulthood. Autosomal-dominant polycystic kidney disease (ADPKD) is by far the most common renal cystic disease. However, there are various cystic kidney diseases, the onset of which occurs at different times in life and depends on the type of the disease and the causative genes involved. When genetic kidney diseases are discussed in the adult setting this view is usually limited on autosomal-dominant kidney disease, the most frequent genetic disorder causing adult onset ESRD. Other diseases—such as autosomal-recessive polycystic kidney disease—are often being viewed as a disorder only important in pediatric nephrology. However, more recent data has revealed that, despite clear age peaks of onset for each disorder, all of them can also show highly variable phenotypes with classical adult onset genetic diseases being of importance in pediatrics and vice versa. Furthermore, the affected children need to be seen by adult nephrologists in the long term after transition, requiring knowledge on the underlying pediatric disease, potential extrarenal manifestations, and genetic counseling. Consequently, the view on these diseases should be widened on both ends. Close interaction between pediatric and adult nephrology is key to appropriate care of patients suffering from genetic kidney disease to profit from each other’s experience.http://journal.frontiersin.org/article/10.3389/fped.2018.00065/fullpolycystic kidney diseasesautosomal dominant polycystic kidney diseaseautosomal-recessive polycystic kidney diseasetuberous sclerosis complexvon Hippel–Lindau diseasenephronophthisis |
| spellingShingle | Roman-Ulrich Müller Thomas Benzing Cystic Kidney Diseases From the Adult Nephrologist’s Point of View Frontiers in Pediatrics polycystic kidney diseases autosomal dominant polycystic kidney disease autosomal-recessive polycystic kidney disease tuberous sclerosis complex von Hippel–Lindau disease nephronophthisis |
| title | Cystic Kidney Diseases From the Adult Nephrologist’s Point of View |
| title_full | Cystic Kidney Diseases From the Adult Nephrologist’s Point of View |
| title_fullStr | Cystic Kidney Diseases From the Adult Nephrologist’s Point of View |
| title_full_unstemmed | Cystic Kidney Diseases From the Adult Nephrologist’s Point of View |
| title_short | Cystic Kidney Diseases From the Adult Nephrologist’s Point of View |
| title_sort | cystic kidney diseases from the adult nephrologist s point of view |
| topic | polycystic kidney diseases autosomal dominant polycystic kidney disease autosomal-recessive polycystic kidney disease tuberous sclerosis complex von Hippel–Lindau disease nephronophthisis |
| url | http://journal.frontiersin.org/article/10.3389/fped.2018.00065/full |
| work_keys_str_mv | AT romanulrichmuller cystickidneydiseasesfromtheadultnephrologistspointofview AT thomasbenzing cystickidneydiseasesfromtheadultnephrologistspointofview |