Comparative efficacy of placebos in short-term antidepressant trials for major depression: a secondary meta-analysis of placebo-controlled trials

Comparative efficacy of placebos in short-term antidepressant trials for major depression: a secondary meta-analysis of placebo-controlled trials

Abstract Background The issue of unblinded outcome-assessors and patients has repeatedly been stressed as a flaw in allegedly double-blind antidepressant trials. Unblinding bias can for example result from a drug‘s marked side effects. If such unblinding bias is present for a given drug, then it mig...

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Bibliographic Details
Main Authors: Lisa Holper, Michael P. Hengartner
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Psychiatry
Subjects:
Bayesian network meta-analysis
Placebo
Antidepressants
Unblinding
Side-effects
Online Access:http://link.springer.com/article/10.1186/s12888-020-02839-y

Internet

http://link.springer.com/article/10.1186/s12888-020-02839-y

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