Major Depressive Disorder is Associated with Impaired Mitochondrial Function in Skin Fibroblasts

Major Depressive Disorder is Associated with Impaired Mitochondrial Function in Skin Fibroblasts

Mitochondrial malfunction is supposed to be involved in the etiology and pathology of major depressive disorder (MDD). Here, we aimed to identify and characterize the molecular pathomechanisms related to mitochondrial dysfunction in adult human skin fibroblasts, which were derived from MDD patients...

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Bibliographic Details
Main Authors: Kerstin Kuffner, Julian Triebelhorn, Katrin Meindl, Christoph Benner, André Manook, Daniel Sudria-Lopez, Ramona Siebert, Caroline Nothdurfter, Thomas C. Baghai, Konstantin Drexler, Mark Berneburg, Rainer Rupprecht, Vladimir M. Milenkovic, Christian H. Wetzel
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
major depression
skin fibroblasts
mitochondria
bioenergetics
oxidative phosphorylation
adenosine triphosphate
Online Access:https://www.mdpi.com/2073-4409/9/4/884

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