Effect of Chitosan and Aloe Vera Extract Concentrations on the Physicochemical Properties of Chitosan Biofilms
Chitosan films have been extensively studied as dressings in formulations for the treatment of chronic wounds. The incorporation of aloe vera (<i>Aloe barbadensis</i> Miller) into chitosan dressings could potentialize the healing process since aloe vera shows several pharmacological acti...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-04-01
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| Series: | Polymers |
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| Online Access: | https://www.mdpi.com/2073-4360/13/8/1187 |
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| author | Cristiana M. P. Yoshida Murilo S. Pacheco Mariana A. de Moraes Patrícia S. Lopes Patrícia Severino Eliana B. Souto Classius F. da Silva |
| author_facet | Cristiana M. P. Yoshida Murilo S. Pacheco Mariana A. de Moraes Patrícia S. Lopes Patrícia Severino Eliana B. Souto Classius F. da Silva |
| author_sort | Cristiana M. P. Yoshida |
| collection | DOAJ |
| description | Chitosan films have been extensively studied as dressings in formulations for the treatment of chronic wounds. The incorporation of aloe vera (<i>Aloe barbadensis</i> Miller) into chitosan dressings could potentialize the healing process since aloe vera shows several pharmacological activities. This work aimed to evaluate the effect of aloe vera and chitosan concentrations on the physicochemical properties of the developed films. The films were obtained by casting technique and characterized with respect to their color parameters, morphology, barrier and mechanical properties, and thermal analysis. Results showed that the presence of aloe vera modified the films′ color parameters, changed barrier properties, increased fluid handling capacity (FHC), and decreased water-vapor permeability (WVP). The reduced elongation at break resulted in more rigid films. Aloe vera concentration did not significantly change film properties, but the presence of this gel increased the films’ stability at temperatures below 200 °C, showing similar behavior as chitosan films above 400 °C. The results suggest a crosslinking/complexation between chitosan and aloe vera, which combine appropriate physicochemical properties for application as wound dressing materials. |
| first_indexed | 2024-03-10T12:32:37Z |
| format | Article |
| id | doaj.art-24adb08959834044b421050658e3810d |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-03-10T12:32:37Z |
| publishDate | 2021-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-24adb08959834044b421050658e3810d2023-11-21T14:32:49ZengMDPI AGPolymers2073-43602021-04-01138118710.3390/polym13081187Effect of Chitosan and Aloe Vera Extract Concentrations on the Physicochemical Properties of Chitosan BiofilmsCristiana M. P. Yoshida0Murilo S. Pacheco1Mariana A. de Moraes2Patrícia S. Lopes3Patrícia Severino4Eliana B. Souto5Classius F. da Silva6Department of Pharmaceutical Sciences, Institute of Environmental, Chemical and Pharmaceutical Sciences (ICAQF), Federal University of São Paulo (UNIFESP), Diadema, São Paulo 09913-030, BrazilDepartment of Chemical Engineering, Institute of Environmental, Chemical and Pharmaceutical Sciences (ICAQF), Federal University of São Paulo (UNIFESP), Diadema, São Paulo 09913-030, BrazilDepartment of Chemical Engineering, Institute of Environmental, Chemical and Pharmaceutical Sciences (ICAQF), Federal University of São Paulo (UNIFESP), Diadema, São Paulo 09913-030, BrazilDepartment of Pharmaceutical Sciences, Institute of Environmental, Chemical and Pharmaceutical Sciences (ICAQF), Federal University of São Paulo (UNIFESP), Diadema, São Paulo 09913-030, BrazilUniversity of Tiradentes (Unit), Biotechnological Postgraduate Program, Aracaju 49010-390, BrazilCEB-Centre of Biological Engineering, Campus de Gualtar, University of Minho, 4710-057 Braga, PortugalDepartment of Chemical Engineering, Institute of Environmental, Chemical and Pharmaceutical Sciences (ICAQF), Federal University of São Paulo (UNIFESP), Diadema, São Paulo 09913-030, BrazilChitosan films have been extensively studied as dressings in formulations for the treatment of chronic wounds. The incorporation of aloe vera (<i>Aloe barbadensis</i> Miller) into chitosan dressings could potentialize the healing process since aloe vera shows several pharmacological activities. This work aimed to evaluate the effect of aloe vera and chitosan concentrations on the physicochemical properties of the developed films. The films were obtained by casting technique and characterized with respect to their color parameters, morphology, barrier and mechanical properties, and thermal analysis. Results showed that the presence of aloe vera modified the films′ color parameters, changed barrier properties, increased fluid handling capacity (FHC), and decreased water-vapor permeability (WVP). The reduced elongation at break resulted in more rigid films. Aloe vera concentration did not significantly change film properties, but the presence of this gel increased the films’ stability at temperatures below 200 °C, showing similar behavior as chitosan films above 400 °C. The results suggest a crosslinking/complexation between chitosan and aloe vera, which combine appropriate physicochemical properties for application as wound dressing materials.https://www.mdpi.com/2073-4360/13/8/1187aloe verachitosan membranewound healingcolor parametersmoisture vapor transmission ratetensile strength |
| spellingShingle | Cristiana M. P. Yoshida Murilo S. Pacheco Mariana A. de Moraes Patrícia S. Lopes Patrícia Severino Eliana B. Souto Classius F. da Silva Effect of Chitosan and Aloe Vera Extract Concentrations on the Physicochemical Properties of Chitosan Biofilms Polymers aloe vera chitosan membrane wound healing color parameters moisture vapor transmission rate tensile strength |
| title | Effect of Chitosan and Aloe Vera Extract Concentrations on the Physicochemical Properties of Chitosan Biofilms |
| title_full | Effect of Chitosan and Aloe Vera Extract Concentrations on the Physicochemical Properties of Chitosan Biofilms |
| title_fullStr | Effect of Chitosan and Aloe Vera Extract Concentrations on the Physicochemical Properties of Chitosan Biofilms |
| title_full_unstemmed | Effect of Chitosan and Aloe Vera Extract Concentrations on the Physicochemical Properties of Chitosan Biofilms |
| title_short | Effect of Chitosan and Aloe Vera Extract Concentrations on the Physicochemical Properties of Chitosan Biofilms |
| title_sort | effect of chitosan and aloe vera extract concentrations on the physicochemical properties of chitosan biofilms |
| topic | aloe vera chitosan membrane wound healing color parameters moisture vapor transmission rate tensile strength |
| url | https://www.mdpi.com/2073-4360/13/8/1187 |
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