Exploring the complexities of 1C metabolism: implications in aging and neurodegenerative diseases

Exploring the complexities of 1C metabolism: implications in aging and neurodegenerative diseases

The intricate interplay of one-carbon metabolism (OCM) with various cellular processes has garnered substantial attention due to its fundamental implications in several biological processes. OCM serves as a pivotal hub for methyl group donation in vital biochemical reactions, influencing DNA methyla...

Full description

Bibliographic Details
Main Authors:	Ayman Bou Ghanem, Yaman Hussayni, Raghid Kadbey, Yara Ratel, Shereen Yehya, Lara Khouzami, Hilda E. Ghadieh, Amjad Kanaan, Sami Azar, Frederic Harb
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-01-01
Series:	Frontiers in Aging Neuroscience
Subjects:	one carbon metabolism folate Alzheimer’s disease Parkinson disease aging mitochondrial dysfuntion
Online Access:	https://www.frontiersin.org/articles/10.3389/fnagi.2023.1322419/full

Similar Items

Reno-Protective Effect of GLP-1 Receptor Agonists in Type1 Diabetes: Dual Action on TRPC6 and NADPH Oxidases
by: Natalie Youssef, et al.
Published: (2021-09-01)

Turkish validity and reliability of the sexual complaints screener for men
by: Anıl Gündüz, et al.
Published: (2019-10-01)

Exploring the World of Membrane Proteins: Techniques and Methods for Understanding Structure, Function, and Dynamics
by: Imad Boulos, et al.
Published: (2023-10-01)

Reduced Kidney Function Is Associated with Increasing Red Blood Cell Folate Concentration and Changes in Folate Form Distributions (NHANES 2011–2018)
by: Arick Wang, et al.
Published: (2022-03-01)

Role of Insulin Clearance in Insulin Action and Metabolic Diseases
by: Hilda E. Ghadieh, et al.
Published: (2023-04-01)

Influence of intermittent fasting on prediabetes-induced neuropathy: Insights on a novel mechanistic pathway
by: Maya Dannawi, et al.
Published: (2022-06-01)

Absorption and Tissue Distribution of Folate Forms in Rats: Indications for Specific Folate Form Supplementation during Pregnancy
by: Natasha Bobrowski-Khoury, et al.
Published: (2022-06-01)

Cerebral Folate Deficiency Syndrome: Early Diagnosis, Intervention and Treatment Strategies
by: Vincent Th. Ramaekers, et al.
Published: (2022-07-01)

Vitamin intake and periodontal disease: a meta-analysis of observational studies
by: Nannan Mi, et al.
Published: (2024-01-01)

COC’s application for decreasing cardiovascular risks
by: L. Yu. Karakhalis, et al.
Published: (2019-04-01)

Dietary Intake of Folate and Assessment of the Folate Deficiency Prevalence in Slovenia Using Serum Biomarkers
by: Igor Pravst, et al.
Published: (2021-10-01)

Cerebral Folate Metabolism in Post-Mortem Alzheimer’s Disease Tissues: A Small Cohort Study
by: Naila Naz, et al.
Published: (2022-12-01)

Probable Causes of Alzheimer’s Disease
by: James David Adams
Published: (2021-03-01)

One-Carbon Metabolism: Pulling the Strings behind Aging and Neurodegeneration
by: Eirini Lionaki, et al.
Published: (2022-01-01)

First‐Trimester Maternal Folic Acid Supplementation Reduced Risks of Severe and Most Congenital Heart Diseases in Offspring: A Large Case‐Control Study
by: Yanji Qu, et al.
Published: (2020-07-01)

Randomized controlled trial of hydrolyzed fish diets in dogs with chronic enteropathy
by: Kenneth W. Simpson, et al.
Published: (2023-11-01)

Folate Transport and One-Carbon Metabolism in Targeted Therapies of Epithelial Ovarian Cancer
by: Adrianne Wallace-Povirk, et al.
Published: (2021-12-01)

Brain Uptake of Folate Forms in the Presence of Folate Receptor Alpha Antibodies in Young Rats: Folate and Antibody Distribution
by: Natasha Bobrowski-Khoury, et al.
Published: (2023-02-01)

The Concept of Folic Acid in Health and Disease
by: Yulia Shulpekova, et al.
Published: (2021-06-01)

Novel localization of folate transport systems in the murine central nervous system
by: Vishal Sangha, et al.
Published: (2022-11-01)

Vitamin D and Folate as Predictors of MMSE in Alzheimer’s Disease: A Machine Learning Analysis
by: Giuseppe Murdaca, et al.
Published: (2021-05-01)

Causal Effects of Homocysteine, Folate, and Cobalamin on Kidney Function: A Mendelian Randomization Study
by: Sehoon Park, et al.
Published: (2021-03-01)

Reversal of Lipid Metabolism Dysregulation by Selenium and Folic Acid Co-Supplementation to Mitigate Pathology in Alzheimer’s Disease
by: Zhong-Hao Zhang, et al.
Published: (2022-04-01)

B12 and Folate Concentrations in Opium Addicts Compared to Healthy Subjects: A Case Control Study from Kerman Coronary Artery Disease Risk Study
by: Ahmad Gholamhossenian, et al.
Published: (2018-08-01)

PROTHROMBOTIC POLYMORPHISMS AND LONG-TERM PROGNOSIS OF PATIENTS WITH STABLE ISCHEMIC HEART DISEASE
by: A. L. Komarov, et al.
Published: (2016-01-01)

Serum binding folate receptor autoantibodies lower in autistic boys and positively-correlated with folate
by: Ai Shi, et al.
Published: (2024-03-01)

Design of Folate-Containing Liposomal Nucleic Acid Delivery Systems for Antitumor Therapy
by: Elena V. Shmendel, et al.
Published: (2023-05-01)

The Impact of Maternal Folates on Brain Development and Function after Birth
by: Sapna Virdi, et al.
Published: (2022-09-01)

Design of Cereal Products Naturally Enriched in Folate from Barley Pearling By-Products
by: Stefania Ruggeri, et al.
Published: (2022-09-01)

FOLATE METABOLISM IN PREGNANCY
by: Z.D. SALIMOVA, et al.
Published: (2022-12-01)

A Cross-Sectional Study of Dietary and Genetic Predictors of Blood Folate Levels in Healthy Young Adults
by: Daniel Cummings, et al.
Published: (2017-09-01)

CYP450 Mediates Reactive Oxygen Species Production in a Mouse Model of β-Thalassemia through an Increase in 20-HETE Activity
by: Rayan Bou-Fakhredin, et al.
Published: (2021-01-01)

Ubiquitin Pathways in Neurodegenerative Disease
by: Graham eAtkin, et al.
Published: (2014-07-01)

Genus Boswellia as a new candidate for neurodegenerative disorders
by: Arezoo Rajabian, et al.
Published: (2020-03-01)

Features of Plasma Homocysteine, Vitamin B12, and Folate in Parkinson's Disease: An Updated Meta-Analysis
by: Yiti Liu, et al.
Published: (2023-08-01)

Editorial: Metabolism in nonalcoholic fatty liver disease
by: Sonia Michael Najjar, et al.
Published: (2023-08-01)

biosynthesis of folates by lactic acid bacteria and propionibacteria in fermented milk
by: M. Holasová, et al.
Published: (2004-10-01)

NEUROMODULACIÓN EN PATOLOGÍAS DE PISO PÉLVICO
by: Valentín Manríquez G, et al.
Published: (2010-01-01)

Folate Enrichment of Whole-Meal Spaghetti Using Durum Wheat Debranning Fractions
by: Valentina Di Nardo, et al.
Published: (2023-06-01)

Reply: “Comment on: The Vitamin D–Folate Hypothesis as an Evolutionary Model for Skin Pigmentation: An Update and Integration of Current Ideas, <i>Nutrients</i> <b>2018</b>, <i>10</i>, 554”
by: Patrice Jones, et al.
Published: (2018-11-01)